Using the CAESARE tool in fetal heart rate analysis.

Background: To evaluate the theoretical impact of the CAESARE decision-making tool (which is based on fetal heart rate) on the rate of cesarean section deliveries and the prevention of metabolic acidosis risk.

Methods: We conducted an observational, multicenter, retrospective study of all patients from 2018 to 2020 who had a cesarean section at term due to non-reassuring fetal status (NRFS) during labor. Primary outcome criteria were the rate of cesarean section births observed retrospectively compared to the theoretical rate by the CAESARE tool.

Fine motor impairment in children with epilepsy: Relations with seizure severity and lateralizing value.

Motor skill deficits are common in epilepsy. The Grooved Pegboard Test (GPT) is the most commonly used fine motor task and is included in the NIH Common Data Elements Battery for the assessment of epilepsy. However, there are limited data on its utility in children and adolescents.

Emotional functioning in pediatric epilepsy: Evidence of greater externalizing behavior with left hemisphere onset.

Though it is wellknown that psychiatric concerns are common in children with epilepsy, factors predicting such problems are not well understood. The present investigation studied rates of parent-reported psychological concerns in clinically referred children with epilepsy. Further, it investigated differences in psychological distress across epilepsy subtypes (i.

Ruling out septic arthritis risk in a few minutes using mid-infrared spectroscopy in synovial fluids.

Objectives: The aim of this study was to show the usefulness of a mid-infrared fibre evanescent wave spectroscopy point of care device in the identification of septic arthritis patients in a multicentre cohort, and to apply this technology to clinical practice among physicians.

Methods: SF samples from 402 patients enrolled in a multicentre cohort were frozen for analysis by mid-infrared fibre evanescent wave spectroscopy. The calibration cohort was divided into two groups of patients (septic arthritis and non-septic arthritis) and relevant spectral variables were used for logistic regression model.

Vocal Change Patterns During a Teaching Day: Inter- and Intra-subject Variability.

Objectives: To describe the mean voice changes of 22 female teachers during a typical workday, examine the inter- and intra-subject variability, and establish a typology of different voice patterns during the workday.

Methods: For each participant, fundamental frequency (F0), harmonics-to-noise ratio (HNR), jitter, and shimmer were measured on sustained vowels at the beginning and at the end of the workday, at three different times during the school year.

Results: The group mean pattern showed significant increases in F0 and HNR during the workday and significant decreases in jitter and shimmer.

Combining cytology and microcrystal detection in nonpurulent joint fluid benefits the diagnosis of septic arthritis.

Objective: To evaluate the performance of combined cytology and microcrystal detection in joint fluid for diagnosing septic arthritis.

Methods: Retrospective single-center study of joint fluid samples from patients with manifestations suggesting acute or chronic arthritis. The absolute leukocyte count (/mm) was recorded; as well as the differential counts, particularly of neutrophils (%).

Severe osteoporosis: diagnosis and follow-up. Lessons for clinical practice.

The management of osteoporosis has improved considerably, leading to the development of new goals. A major concern today is the management of patients with severe osteoporosis, in whom the need for pharmacotherapy is clear [1]. Epidemiological data have established that osteoporosis is associated with severe complications [2,3].

Management of patients with incident fractures during osteoporosis treatment.

Official recommendations are available for detecting osteoporosis and initiating osteoporosis medications in postmenopausal women. However, there are no recommendations about the management of patients with incident fractures despite osteoporosis therapy. Second-line osteoporosis treatments have been evaluated only based on laboratory and absorptiometry criteria.

Defining treatment failure in severe osteoporosis.

The management of postmenopausal osteoporosis has benefited from the recent introduction of several new drug classes and is now well standardized. However, none of the available osteoporosis drugs completely abolishes the occurrence of fractures. Therefore, criteria are needed to determine when the occurrence of a fracture during treatment indicates failure to respond to the drug.

Stabilized severe osteoporosis: should the treatment be stopped?

Several medications have been proven to decrease the risk of postmenopausal osteoporotic fractures of the spine, hip, or peripheral skeleton. However, the optimal duration of treatment with these medications has not been determined. The efficacy data come chiefly from controlled trials conducted over 3 to 5 years in elderly women at high risk for fractures.

Severe osteoporosis: does structural monitoring help?

Vertebral fractures, the most common osteoporotic fractures, are associated with excess mortality even in the absence of symptoms. Presence of at least one radiological or clinical prevalent vertebral fracture increases the risk of incident vertebral fractures not only in untreated patients, but also in treated patients, as established by studies involving routine radiological monitoring. Therefore, whether structural monitoring is indicated on a routine basis deserves discussion.

Osteoporosis and mortality.

Osteoporosis is classified as a public health problem by healthcare authorities because it is associated with an increased risk of potentially serious fractures. Osteoporotic fractures are known to generate a heavy burden of morbidity and financial cost [1]. However, recent data indicate that some osteoporotic fractures are also associated with excess mortality.

Severity of osteoporosis: what is the impact of co-morbidities?

The co-morbidity profile varies widely across postmenopausal women with osteoporosis, and comorbidities often adversely affect the management of osteoporosis. There is a need for detailed information on the co-morbidities that may affect the course of osteoporosis by increasing the risk of subsequent fractures or inducing multiple fractures. We consequently reviewed the literature on the most common co-morbidities in adults older than 50 years of age, with special attention to published meta-analyses.

[Information needs of families of children with a disability: the viewpoint of parents and health professionals].

This preliminary study aimed at documenting the needs of families having a child with a disability concerning information, from the point of view of both parents and professionals involved with them. Three discussion groups were carried out: two with parents of children with Down's syndrome or cerebral palsy, and another group with health professionals involved with them. The results show that the parents are searching for information concerning the initial health problem, the available health care and other resources that might be of help.