Publications by authors named "Claire D Wathes"
BMC Genomics
September 2021
Article Synopsis
- This study investigates how immune pathways in dairy cows change with age, focusing on Holstein cows in early lactation, to identify factors that influence longevity and health as they age.
- Three groups of cows based on lactation number (primiparous, multiparous 2-3, and multiparous 4-7) were analyzed to compare gene expression in leukocytes, revealing seven modules linked to lactation number and distinct expression patterns for various gene clusters.
- Key findings show that genes more active in primiparous cows are linked to gene transcription regulation and mitochondrial functions, while multiparous cows exhibit higher expression of genes related to glycolysis, immunity, and immune defense, highlighting age
