A 46-year-old woman presented at the emergency department because of acute hepatitis with jaundice. After hepatological work-up including liver biopsy, drug induced liver disease (DILI) was suspected. Patient recovered completely within a few months.
View Article and Find Full Text PDFBackground: Central aortic stiffness is established as a reliable measure of cardiovascular disease. While pulse wave velocity (PWV) analysis measures arterial distensibility, risk profile of cardiovascular diseases can be expanded with following pulse wave analysis measurements: central aortic systolic blood pressure (CABPS), central aortic pulse pressure (CAPP), central aortic reflection magnitude (CARM), central aortic augmented pressure (CAAP) and central aortic augmentation index (CAAIx). The aim of this study is to evaluate the clinical usefulness and importance of pulse wave analysis measurements in specific cardiovascular conditions and diseases, both in term of diagnosis and therapeutic monitoring.
View Article and Find Full Text PDFWe present a new measurement of the positive muon magnetic anomaly, a_{μ}≡(g_{μ}-2)/2, from the Fermilab Muon g-2 Experiment using data collected in 2019 and 2020. We have analyzed more than 4 times the number of positrons from muon decay than in our previous result from 2018 data. The systematic error is reduced by more than a factor of 2 due to better running conditions, a more stable beam, and improved knowledge of the magnetic field weighted by the muon distribution, ω[over ˜]_{p}^{'}, and of the anomalous precession frequency corrected for beam dynamics effects, ω_{a}.
View Article and Find Full Text PDFThe absolute scale of the neutrino mass plays a critical role in physics at every scale, from the subatomic to the cosmological. Measurements of the tritium end-point spectrum have provided the most precise direct limit on the neutrino mass scale. In this Letter, we present advances by Project 8 to the cyclotron radiation emission spectroscopy (CRES) technique culminating in the first frequency-based neutrino mass limit.
View Article and Find Full Text PDFActa Gastroenterol Belg
October 2021
Patients And Methods: A prospective registration of patients with colorectal cancer and a colonoscopy within the last 10 years. We tried to classify these post-colonoscopy colorectal cancers (PCCRCs) by most reasonable explanation and into subcategories suggested by the World Endoscopy Organization (WEO) and calculated the unadjusted PCCRC rate.
Results: 47 PCCRCs were identified.
Objectives: The objective of this study was to compare maxillary dimensions and growth in newborns with Complete Unilateral Cleft Lip and Palate (UCLP) to healthy newborns before and after cheiloplasty. Additionally, a palatal growth curve is constructed to give more information about the natural growth before surgical intervention.
Methods: Twenty-eight newborns with complete UCLP were enrolled in this study.
The beta decay of tritium in the form of molecular T_{2} is the basis of sensitive experiments to measure neutrino mass. The final-state electronic, vibrational, and rotational excitations modify the beta spectrum significantly and are obtained from theory. We report measurements of the branching ratios to specific ionization states for the isotopolog HT.
View Article and Find Full Text PDFUnsymmetrical subphthalocyanine fused dimers have been prepared from appropriate -dinitrile SubPc precursors. In particular, either electron-donating or electron-accepting substituents have been introduced on each SubPc constituent unit, resulting in unprecedented push-pull π-extended curved aromatic macrocycles. From fluorescence experiments in solvents of different polarity we conclude a dual fluorescence, namely a delocalized singlet excited state (1.
View Article and Find Full Text PDFA series of subphthalocyanines (SubPcs) bearing a carboxylic acid group either at the peripheral or axial position have been designed and synthesized to investigate the influence of the COOH group positions on the dye-sensitized solar cell (DSSC) performance. The DSSC devices based on SubPcs with axially substituted carboxylic acid groups showed low photovoltaic performance, whereas peripherally substituted one exhibited higher power conversion efficiency owing to improved injection from LUMO of SubPcs to the TiO2 conduction band.
View Article and Find Full Text PDFFour new subphthalocyanine-based capsules have been synthesized and characterized. These supramolecular systems have been successfully employed for the encapsulation of fullerenes and probed by a wide range of characterization methods, including NMR, UV-vis and fluorescence spectroscopy, electrospray ionization mass spectrometry, and electrochemistry. Furthermore, the binding constants of the host guest complexes were estimated.
View Article and Find Full Text PDFA comparative study of the relative stability of subphthalocyanine metallosupramolecular capsules bearing different metals and ligands has been carried out by electrospray ionization quadrupole time-of-flight tandem mass spectrometry experiments. The results highlight the trends in the strength of metal-nitrogen bonds as well as the 'trans effect' of certain ligands.
View Article and Find Full Text PDFObjective: The aim of the study was to identify the most relevant literature on skills, attitude and behaviour of children and young people towards the use of an automated external defibrillator (AED) and then develop recommendations according to the principles of evidence-based practice. These recommendations were to serve as a basis for educational materials which would ensure that the implementation of AED-training within schools and youth organisations would be a simple process.
Methods: A systematic literature search was performed using a specific research question: "Are children of different ages able/willing to use an AED after a training compared to another/no training?".
Background: Rapid and point-of-care (POC) tests for syphilis are an invaluable screening tool, yet inadequate evaluation of their diagnostic accuracy against best reference standards limits their widespread global uptake. To fill this gap, a systematic review and meta-analysis was conducted to evaluate the sensitivity and specificity of rapid and POC tests in blood and serum samples against Treponema pallidum (TP) specific reference standards.
Methods: Five electronic databases (1980-2012) were searched, data was extracted from 33 articles, and Bayesian hierarchical models were fit.
One carbon atom is too many. Two subphthalocyanine-extended TTF electron donor-acceptor conjugates were synthesized and characterized. Their photophysical properties prompt the remarkable impact that one extra carbon between the two constitutents exerts on photoinduced processes, that is, charge recombination dynamics in the normal versus inverted region.
View Article and Find Full Text PDFBackground: The focus on prevention strategies aimed at curbing the HIV epidemic is growing, and therefore screening for HIV has again taken centre stage. Our aim was to establish whether a convenient, non-invasive, HIV test that uses oral fluid was accurate by comparison with the same test with blood-based specimens.
Methods: We did a systematic review and meta-analysis to compare the diagnostic accuracy of a rapid HIV-antibody-based point-of-care test (Oraquick advance rapid HIV-1/2, OraSure Technologies Inc, PA, USA) when used with oral versus blood-based specimens in adults.
Background: Elective switching between anti-tumour necrosis factor (TNF) agents not necessarily dictated by efficacy or tolerability occurs in clinical practice. A study was undertaken to evaluate prospectively the impact of elective switching of patients with Crohn's disease well controlled with intravenous infliximab to subcutaneous adalimumab in a controlled trial.
Methods: An open-label randomised single-centre trial recruited 73 patients with ongoing response to at least 6 months of scheduled maintenance infliximab.
The synthesis of a new subphthalocyanine is reported. Its structural and photophysical properties are ideal for probing the accessibility of arrays of silica nanochannels.
View Article and Find Full Text PDFObjectives: To investigate temporal trends in HIV incidence rates and to assess changes over time in associated risk factors.
Methods: Since 1995, the SurvUDI network has conducted surveillance among IDUs recruited in harm reduction programmes in eastern central Canada. Among the 11,731 participants, 2903 repeaters were initially HIV-negative.
Ultra high vacuum scanning tunnelling microscopy revealed chlorosubphthalocyanine to self-organize into discrete well-defined bilayer and trilayer triangular nanocrystallites when evaporated onto a Cu(111) surface.
View Article and Find Full Text PDFCardiac rehabilitation improves the subjective condition of the patient; but are there associated structural and functional cardiac adaptations? The study group consisted of 39 patients with an inferior infarction and 21 patients with an anterior infarction, treated by surgical revascularization followed by 4 months of cardiac rehabilitation. Maximal exercise testing and Doppler echocardiography were performed before and after the rehabilitation program. Performance capacity was significantly improved after cardiac rehabilitation, but left ventricular function remained unchanged on Doppler imaging.
View Article and Find Full Text PDFA kinetic mixture of self-assembled subphthalocyanine-based capsules was shown to gradually reorganize into its more stable symmetrical components by electrospray mass spectrometry.
View Article and Find Full Text PDFWe have designed, synthesized and probed a dodecafluoro-subphthalocyaninato boron(III) unit, which bears a triphenylamine moiety in its axial position, as a novel electron donor-acceptor system.
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