Publications by authors named "Citing Zhang"
Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant and lethal human cancers in the world due to its high metastatic potential, and patients with PDAC have a poor prognosis, yet quite little is understood regarding the underlying biological mechanisms of its high metastatic capacity. Baicalein has a dramatic anti-tumor function in the treatment of different types of cancer. However, the therapeutic effects of baicalein on human PDAC and its mechanisms of action have not been extensively understood.
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- Colon cancer (COAD) significantly contributes to global cancer deaths, primarily due to its tendency to metastasize, although the mechanisms behind this are not fully understood.
- The tumor microenvironment (TME) plays a crucial role in COAD progression and may offer insight into its metastatic behavior, with a specific TME Regulatory Network identified that includes AEBP1, BGN, POST, and FAP—this network correlates with COAD severity and immune infiltration.
- Dihydroartemisinin (DHA) has the potential to interact with this regulatory network, suggesting it may help regulate immune responses in COAD, which could lead to improved prognostic and therapeutic strategies for managing the disease.