Texture Analysis of Dried Droplets for the Quality Control of Medicines.

The quality control of medicines guarantees the effectiveness of treatments for diseases. We explore the use of texture analysis of patterns in dried droplets as a tool to readily detect both impurities and changes in drug concentration. Four types of medicines associated with different routes of administration were analyzed: Methotrexate, Ciprofloxacin, Clonazepam, and Budesonide.

Effects of substrate temperature on patterns produced by dried droplets of proteins.

Rapid diagnosis provides better clinical management of patients, helps control possible outbreaks, and increases survival. The study of deposits produced by the evaporation of droplets is a useful tool in the diagnosis of some health problems. With the aim to improve diagnostic time in clinical practice where we use the evaporation of droplets, we explored the effects of substrate temperature on pattern formation of dried droplets in globular protein solutions.

Feasibility of the use of a pixelated transmission chamber to measure scattered-radiation in projection radiography: I. Monte Carlo analysis of x-ray scatter propagation and detector modeling.

In this paper, we propose the use of a pixelated transmission chamber, placed between the patient and the imaging detector, to measure the scatter component of a radiation beam impinging on said imaging detector. Using Monte Carlo simulation, a three-parameter model for the propagation of the scatter component in the transmitted beam is first developed. The use of the transmission chamber to determine the model parameters is then modeled, again using Monte Carlo simulation, and the feasibility of this approach is determined.