Tuberculosis remains a public health problem in Romania.

Background: Tuberculosis (TB) remains a major public health problem in Romania, which has the highest TB incidence in the European Union.

Methods: We undertook a retrospective study to describe changing trends in the main epidemiological indicators of TB in Romania from 1995 to 2016. Data were obtained from the Marius Nasta Institute of Pneumology, Bucharest, official data published by the National Center for Public Health Statistics and Informatics in Health Statistics Yearbooks, the European Health For All database and the World Health Organization 2017 global TB report.