Publications by authors named "Cinzia Quarti"
Background Aims: The Pall Celeris system is a filtration-based point-of-care device designed to obtain a high concentrate of peripheral blood total nucleated cells (PB-TNCs). We have characterized the Pall Celeris-derived TNCs for their in vitro and in vivo angiogenic potency.
Methods: PB-TNCs isolated from healthy donors were characterized through the use of flow cytometry and functional assays, aiming to assess migratory capacity, ability to form capillary-like structures, endothelial trans-differentiation and paracrine factor secretion.
We observed a significant increase of Pseudomonas aeruginosa bacteremias during 2002. Eighty-five microbiological samples were taken from different potential sources of infection. Twenty-nine out of 46 specimens obtained from water taps, shower heads and siphons tested positive for Pseudomonas aeruginosa.
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- The study analyzed lymphocyte subsets in 20 packed red blood cell units before and after using the Pall Leukotrap RC inline filter system, dividing samples into two groups based on preparation methods.
- Group A (low spin/PRP removal) had significantly higher median white blood cell (WBC) counts compared to Group B (high spin/plasma and buffy-coat removal), with p < 0.0001 indicating a strong statistical difference.
- After filtration, lymphocyte counts, especially CD3+, CD3+CD4+, and CD3+CD8+ subsets, were reduced significantly, with all CD19+ lymphocytes dropping below the limit of detection in all units.