Publications by authors named "Cintia Estefano Alves"
Article Synopsis
- Chronic Obstructive Pulmonary Disease (COPD) significantly affects global health, with factors such as smoking and immune cell profiles contributing to its severity; a deficiency in specific regulatory T cells can worsen respiratory issues.
- Researchers employed Photobiomodulation (PBM) therapy to investigate its effects on immune response in a COPD mouse model by analyzing various immune cell types and cytokine production.
- The findings indicated that PBM therapy alleviated COPD symptoms by reducing inflammatory immune cell counts, lowering pro-inflammatory cytokines like IFN-γ, and boosting the anti-inflammatory cytokine IL-10, suggesting a potential treatment avenue for COPD.
Photobiomodulation Therapy Restores IL-10 Secretion in a Murine Model of Chronic Asthma: Relevance to the Population of CD4CD25Foxp3 Cells in Lung.
Front Immunol
April 2022
It is largely known that photobiomodulation (PBM) has beneficial effects on allergic pulmonary inflammation. Our previous study showed an anti-inflammatory effect of the PBM in an acute experimental model of asthma, and we see that this mechanism is partly dependent on IL-10. However, it remains unclear whether the activation of regulatory T cells is mediated by PBM in a chronic experimental model of asthma.
View Article and Find Full Text PDFLow-level laser therapy attenuates lung inflammation and airway remodeling in a murine model of idiopathic pulmonary fibrosis: Relevance to cytokines secretion from lung structural cells.
J Photochem Photobiol B
January 2020
Idiopathic pulmonary fibrosis (IPF) is a progressive and chronic inflammatory disease with a poor prognosis and very few available treatment options. Low-level laser therapy (LLLT) has been gaining prominence as a new and effective anti-inflammatory and immunomodulatory agent. Can lung inflammation and the airway remodeling be regulated by LLLT in an experimental model of IPF in C57Bl/6 mice? The present study investigated if laser attenuates cellular migration to the lungs, the airway remodeling as well as pro-fibrotic cytokines secretion from type II pneumocytes and fibroblasts.
View Article and Find Full Text PDFAsthma is characterized by chronic inflammation in the airways. Several models have been proposed for the discovery of new therapies. Low-Level Laser Therapy (LLLT) is relatively new and effective, very low cost, with no side effects.
View Article and Find Full Text PDFLow-Level Laser Therapy Reduces Lung Inflammation in an Experimental Model of Chronic Obstructive Pulmonary Disease Involving P2X7 Receptor.
Oxid Med Cell Longev
September 2018
Article Synopsis
- Chronic obstructive pulmonary disease (COPD) is a serious, progressive illness causing irreversible airflow issues and is one of the top causes of death globally, creating significant economic burdens.
- Low-level laser therapy (LLLT) has emerged as a potential treatment option, known for its cost-effectiveness and lack of side effects, prompting researchers to explore its effectiveness in reducing lung damage from COPD.
- In experimental studies with mice exposed to cigarette smoke, LLLT showed promising results in lowering inflammation and improving lung function by reducing harmful cytokines and collagen buildup while increasing beneficial IL-10 levels.