This study focused on evaluating the influence of geometric dimensions on the drug release kinetics of 3D-printed tablets. An ink based on Gelucire 50/13 was prepared to print ivermectin-loaded tablets. The ink was characterized physicochemically and tablet dissolution tests were carried out.
View Article and Find Full Text PDFUnderstanding a drug dissolution process from solid dispersions (SD) to develop formulations with predictable performance. Dissolution data of fenbendazole released from the SDs and the control physical mixtures were analyzed using the Lumped mathematical model to estimate the parameters of pharmaceutical relevance. The fit data obtained by Lumped model showed that all SDs have a unique dissolution profile with an error of ±4.
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