Publications by authors named "Cinthya Pena-Orbea"
Article Synopsis
- The study investigates how different sleep-related symptoms and patterns (phenotypes) relate to the risk of developing atrial fibrillation (AF) over time.
- Researchers analyzed data from over 43,000 patients who underwent sleep studies, identifying five distinct sleep phenotypes and assessing their impact on AF incidence.
- Results showed that specific phenotypes, particularly the hypoxia and apneas + arousals subtypes, significantly increased the risk of developing AF, highlighting the importance of sleep disorders in heart health.
Background: No therapy has been shown to reduce the risk of major adverse cardiovascular events (MACE) and death in patients with obstructive sleep apnea (OSA).
Objectives: The authors sought to investigate the long-term relationship between metabolic surgery and incident MACE in patients with OSA and obesity.
Methods: Adult patients with a body mass index 35 to 70 kg/m and moderate-to-severe OSA at a U.
Article Synopsis
- A large clinical study was conducted at the Cleveland Clinic to investigate the links between sleep-disordered breathing, sleep-related hypoxia, and the development of atrial fibrillation (AF) over a 5-year period.
- The study analyzed data from over 42,000 patients, finding that increased apnea hypopnea index and lower oxygen saturation significantly raised the risk of developing AF.
- The results indicate that sleep-related hypoxia is a critical factor in the onset of AF, remaining significant even after accounting for pulmonary health metrics.
Background: Few studies have investigated sex-specific disparities in inpatient sleep testing. We postulate that women are more likely to have a milder degree of obstructive sleep apnea (OSA) and lower extent of hypoxia on Type III sleep studies versus polysomnography (PSG).
Patients And Methods: The Cleveland Clinic Sleep laboratory registry was leveraged to identify all adult inpatient sleep studies performed for OSA.
Importance: The influence of sleep-disordered breathing (SDB) and sleep-related hypoxemia in SARS-CoV-2 viral infection and COVID-19 outcomes remains unknown. Controversy exists regarding whether to continue treatment for SDB with positive airway pressure given concern for aerosolization with limited data to inform professional society recommendations.
Objective: To investigate the association of SDB (identified via polysomnogram) and sleep-related hypoxia with (1) SARS-CoV-2 positivity and (2) World Health Organization (WHO)-designated COVID-19 clinical outcomes while accounting for confounding including obesity, underlying cardiopulmonary disease, cancer, and smoking history.
Study Objectives: Treatment of sleep-disordered breathing may improve health-related outcomes postdischarge. However timely definitive sleep testing and provision of ongoing therapy has been a challenge. Little is known about how the time of testing-during hospitalization vs after discharge-affects important outcomes such as treatment adherence.
View Article and Find Full Text PDFStudy Objectives: The prevalence and mechanism of medication errors have been well characterized in the literature. However, no prior studies have investigated the frequency and characteristics of errors in the positive airway pressure (PAP) therapy provisioning process when treating patients with sleep-disordered breathing. Just as medication errors may result in unwanted outcomes, it might be anticipated that errors in providing PAP to patients might lead to suboptimal outcomes.
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