Publications by authors named "Cinthya Estefhany Diaz-Benitez"
The immune response to SARS-CoV-2 has been extensively studied following the pandemic outbreak in 2020; however, the presence of specific T cells against SARS-CoV-2 before vaccination has not been evaluated in Mexico. In this study, we estimated the frequency of T CD4+ and T CD8+ cells that exhibit a specific response to S (spike) and N (nucleocapsid) proteins in a Mexican population. We collected 78 peripheral blood samples from unvaccinated subjects, and the presence of antibodies against spike (RBD) and N protein was determined.
View Article and Find Full Text PDFChronic low-grade inflammation (CLI) is implicated in the development of multiple metabolic diseases. The gut microbiota (GM) activates different signaling pathways and induces phenotypic changes, offering an exciting opportunity to treat CLI. We evaluated the mediation of waist circumference on the association of GM with serum cytokines.
View Article and Find Full Text PDFBackground: Imbalance in the intestinal microbiota can lead to chronic low-grade inflammation. Diet may influence this association. In this study, we aimed to evaluate the interaction between () and dietary patterns using a proinflammatory index.
View Article and Find Full Text PDFBackground: Persistent gut microbiota (GM) imbalance has been associated with metabolic disease development. This study evaluated the mediating role of waist circumference in the association between GM and insulin resistance (IR) in children.
Methods: This cross-sectional study included 533 children aged between 6 and 12.
Severe Quantitative Scale of Acanthosis Nigricans in Neck is Associated with Abdominal Obesity, HOMA-IR, and Hyperlipidemia in Obese Children from Mexico City: A Cross-Sectional Study.
Dermatol Res Pract
March 2022
Article Synopsis
- - Acanthosis nigricans (AN) is linked to obesity and may indicate cardiometabolic disorders; this study explores whether the severity of AN in children can help in screening for these issues.
- - The research focused on 95 obese school-age children in Mexico City, using Burke's scale to evaluate AN severity, along with anthropometric and biochemical measurements to assess their health status.
- - Results showed that higher AN severity was associated with increased blood pressure, triglycerides, and decreased adiponectin, suggesting it may be a useful tool for identifying at-risk children and preventing obesity-related complications.
Article Synopsis
- - The study aimed to explore the relationship between gut microbiota composition and childhood obesity, focusing on how different diets influence this connection.
- - Analysis of 46 children classified as normal-weight, overweight, or obese revealed that certain gut bacteria, like Holdemania spp., were linked to lower obesity measures when a high-protein and complex carb diet was consumed.
- - Conversely, bacteria such as Coprococcus catus and others were associated with increased obesity measures when children consumed diets high in saturated fats and simple carbs, suggesting that diet and gut microbiota together may impact childhood obesity.
Article Synopsis
- * It analyzed data from 1142 children, measuring their body metrics and gut microbiota composition, finding that certain gut bacteria relate positively to cholesterol and negatively to triglycerides.
- * Additionally, the study identifies that specific inflammatory markers (IL-6 and IL-10) influence glucose and cholesterol levels, suggesting that body mass index (BMI) plays a key role in these health risks.
Gut microbiota is associated with the development of metabolic disorders. To study its association with childhood obesity, we performed a cross-sectional study with 46 children (6-12 years old). We collected fecal samples, food-frequency questionnaires (FFQs), and anthropometric measurements.
View Article and Find Full Text PDFThis study examined the association between intestinal lactobacilli and obesity dependent on dietary patterns in children. A cross-sectional study was conducted including 1111 children, 6-12 years old. Obesity was determined according to the WHO cut-off points.
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