Computational analysis of variability and uncertainty in the clinical reference on magnetic resonance imaging radiomics: modelling and performance.

To conduct a computational investigation to explore the influence of clinical reference uncertainty on magnetic resonance imaging (MRI) radiomics feature selection, modelling, and performance. This study used two sets of publicly available prostate cancer MRI = radiomics data (Dataset 1: n = 260; Dataset 2: n = 100) with Gleason score clinical references. Each dataset was divided into training and holdout testing datasets at a ratio of 7:3 and analysed independently.

Evaluation of the Reliability and the Performance of Magnetic Resonance Imaging Radiomics in the Presence of Randomly Generated Irrelevant Features for Prostate Cancer.

Radiomics has the potential to aid prostate cancer (PC) diagnoses and prediction by analyzing and modeling quantitative features extracted from clinical imaging. However, its reliability has been a concern, possibly due to its high-dimensional nature. This study aims to quantitatively investigate the impact of randomly generated irrelevant features on MRI radiomics feature selection, modeling, and performance by progressively adding randomly generated features.

Oral self-care among dependent older New Zealanders.

Objectives: The objective of the study was to describe the occurrence and associations of oral self-care by dependent older New Zealanders.

Background: Dependent older adults who require some level of assisted daily care have been shown to have poorer oral health than their independent counterparts, yet national estimates are lacking.

Materials And Methods: A secondary analysis was conducted of data from New Zealand's 2012 Older People's Oral Health Survey, a national survey that interviewed and examined a representative sample of 2,218 dependent older adults living in aged residential care or receiving home-based care.

A pilot study of MRI radiomics for high-risk prostate cancer stratification in 1.5 T MR-guided radiotherapy.

Purpose: To investigate the potential value of MRI radiomics obtained from a 1.5 T MRI-guided linear accelerator (MR-LINAC) for D'Amico high-risk prostate cancer (PC) classification in MR-guided radiotherapy (MRgRT).

Methods: One hundred seventy-six consecutive PC patients underwent 1.

Determining the reliable feature change in longitudinal radiomics studies: A methodological approach using the reliable change index.

Purpose: Determination of reliable change of radiomics feature over time is essential and vital in delta-radiomics, but has not yet been rigorously examined. This study attempts to propose a methodological approach using reliable change index (RCI), a statistical metric to determine the reliability of quantitative biomarker changes by accounting for the baseline measurement standard error, in delta-radiomics. The use of RCI was demonstrated with the MRI data acquired from a group of prostate cancer (PCa) patients treated by 1.

3D-T2W-TSE radiotherapy treatment planning MRI using compressed sensing acceleration for prostate cancer: Image quality and delineation value.

Purpose: To assess the image quality and delineation value of compressed sensing (CS)-accelerated 3D T2W turbo-spin-echo (TSE) sequence for radiotherapy treatment planning (RTP) of prostate cancer.

Methods: An optimized CS-accelerated 3D-T2W-TSE was determined by volunteer imaging and applied for clinical RTP-MRI. This optimized CS-accelerated planning MRI and the standardized adaptive MRI acquired at 1.

Radiomics feature reliability assessed by intraclass correlation coefficient: a systematic review.

Radiomics research is rapidly growing in recent years, but more concerns on radiomics reliability are also raised. This review attempts to update and overview the current status of radiomics reliability research in the ever expanding medical literature from the perspective of a single reliability metric of intraclass correlation coefficient (ICC). To conduct this systematic review, Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed.

Reliability of MRI radiomics features in MR-guided radiotherapy for prostate cancer: Repeatability, reproducibility, and within-subject agreement.

Purpose: The MR-guided radiotherapy (MRgRT) images on the integrated MRI and linear accelerator (MR-LINAC) might facilitate radiomics analysis for longitudinal treatment response assessment. However, the reliability of MRgRT radiomics features is largely unknown. This study aims to investigate MRgRT radiomics feature reliability acquired using a standardized 3D-T2W-TSE sequence in terms of repeatability, reproducibility, and within-subject feature agreement on a 1.

3D T1-weighted turbo spin echo contrast-enhanced MRI at 1.5 T for frameless brain metastases radiotherapy.

Purpose: Performance of 3D-T1W-TSE has been proven superior to 3D-MP-GRE at 3 T on brain metastases (BM) contrast-enhanced (CE) MRI. However, its performance at 1.5 T is largely unknown and sparsely reported.

Emergency physician perspectives on initiating buprenorphine/naloxone in the emergency department: A qualitative study.

Objectives: The objective of this study was to examine the perspectives of Canadian emergency physicians on the care of patients with opioid use disorders in the emergency department (ED), in particular the real-world facilitators to prescribing buprenorphine/naloxone (BUP) in the ED.

Methods: We conducted semistructured qualitative interviews using a multi-site-focused ethnographic design. Purposive sampling via an existing national research network was used to recruit ED physicians.

Quantitative assessment of acquisition imaging parameters on MRI radiomics features: a prospective anthropomorphic phantom study using a 3D-T2W-TSE sequence for MR-guided-radiotherapy.

Background: MRI pulse sequences and imaging parameters substantially influence the variation of MRI radiomics features, thus impose a critical challenge on MRI radiomics reproducibility and reliability. This study aims to prospectively investigate the impact of various imaging parameters on MRI radiomics features in a 3D T2-weighted (T2W) turbo-spin-echo (TSE) pulse sequence for MR-guided-radiotherapy (MRgRT).

Methods: An anthropomorphic phantom was scanned using a 3D-T2W-TSE MRgRT sequence at 1.

Reliability of radiomics features due to image reconstruction using a standardized T -weighted pulse sequence for MR-guided radiotherapy: An anthropomorphic phantom study.

Purpose: To prospectively investigate the impact of image reconstruction on MRI radiomics features.

Methods: An anthropomorphic phantom was scanned at 1.5 T using a standardized sequence for MR-guided radiotherapy under SENSE and compressed-SENSE reconstruction settings.

Extracting extensor digitorum communis activation patterns using high-density surface electromyography.

The extensor digitorum communis muscle plays an important role in hand dexterity during object manipulations. This multi-tendinous muscle is believed to be controlled through separate motoneuron pools, thereby forming different compartments that control individual digits. However, due to the complex anatomical variations across individuals and the flexibility of neural control strategies, the spatial activation patterns of the extensor digitorum communis compartments during individual finger extension have not been fully tracked under different task conditions.