Publications by authors named "Cindy Velazquez-Velazquez"
Article Synopsis
- Head and neck squamous cell carcinomas (HNSCC) exhibit diverse features influenced by human papillomavirus (HPV) status, highlighting the need for careful patient stratification in Mexico.
- A study analyzing 414 Mexican patients revealed that 32.3% tested positive for p16 and 22.3% for HPV, with HPV types 16, 18, and others being the most common.
- High expression levels of certain genes were linked to poor survival rates, while others indicated better outcomes, and specific signaling pathways were found to be downregulated in HPV-positive cases, providing potential targets for therapy.
Background: The aetiological relationship between human papillomavirus (HPV) infection and cervical cancer (CC) is widely accepted. Our goal was to determine the prevalence of HPV types in Mexican women attending at the Mexican Institute for Social Security from different areas of Mexico.
Materials And Methods: DNAs from 2,956 cervical samples were subjected to HPV genotyping: 1,020 samples with normal cytology, 931 with low-grade squamous intraepithelial lesions (LGSIL), 481 with high grade HGSIL and 524 CC.