Publications by authors named "Cindy San"

Purpose: Surgical treatment of severe adolescent idiopathic scoliosis (AIS) with posterior spinal instrumentation and fusion with pedicle screws is common, requiring careful screw insertion to prevent pedicle breaches and neurologic complications. Image guidance has been suggested to improve breach rates, though the radiation risk for AIS precludes its common usage. The purpose of this systematic review and meta-analysis was to compare the breach rates and screw-related complications for AIS patients undergoing spine surgery with pedicle screws between freehand screw insertion and image guidance methods.

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Article Synopsis
  • Clozapine, an antipsychotic for treatment-resistant schizophrenia, can cause severe side effects like myocarditis, prompting this study to assess its occurrence rates in a large hospital setting.
  • The researchers reviewed medical records of 316 patients from January 2010 to July 2016, finding 10 cases of clozapine-induced myocarditis, yielding an incidence rate of 3.16%, with notable symptoms like reduced left ventricular function in 60% of cases.
  • The findings align with the higher end of previously reported rates, highlighting a need for further investigation into risk factors and management strategies for this serious adverse reaction.
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Background: For patients with supratherapeutic international normalized ratio (INR) and no evidence of bleeding, the 2012 guidelines of the American College of Chest Physicians discourage administration of vitamin K. At the study hospital, it was observed that vitamin K was frequently prescribed for patients with INR of 4.5 or higher and no bleeding.

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Background Context: Severe adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity requiring surgery to stop curve progression. Posterior spinal instrumentation and fusion with pedicle screws is the standard surgery for AIS curve correction. Vascular and neurologic complications related to screw malpositioning are concerns in surgeries for AIS.

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Background: Inaccurate documentation of medication histories may lead to medication discrepancies during hospital admissions. Obtaining a best possible medication history (BPMH) for warfarin can be challenging because of frequent dosage changes and nonspecific directions of use (e.g.

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