Publications by authors named "Cindy Germaine Boer"
Background: Identification of modifiable risk factors and treatments for osteoarthritis (OA) are needed. Warfarin, a vitamin K antagonist, causes fetal and animal model skeletal abnormalities. Vitamin K insufficiency has been associated with OA, but whether warfarin is also detrimental to OA is not known.
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- Despite progress in understanding osteoarthritis (OA), only a few genetic loci related to hand OA have been identified due to the complexity of the disease.
- Researchers utilized data from the Rotterdam Study and the Framingham Heart Study to uncover hand OA phenotypes and discover new genetic associations.
- The study found a novel genetic locus on chromosome 1 linked to hand OA, revealing that certain genetic factors are associated with OA across different joints.