Publications by authors named "Cindy Albert"

Article Synopsis
  • The study aims to evaluate how effectively the thickness of different macular retinal layers can differentiate glaucomatous eyes and glaucoma suspects from healthy eyes using optical coherence tomography (OCT).
  • The findings reveal that the nerve fiber layer (NFL) and ganglion cell layer (GCL) have the best diagnostic accuracy, with the ganglion cell complex (GCC) performing similarly, while the inner plexiform layer (IPL) is less effective. The combination of NFL or GCL yields the highest sensitivity and overall diagnostic performance.
  • The results underscore the necessity of assessing individual retinal layers rather than relying solely on combined metrics, as the best-performing layers can vary based on the specific area of the retina
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The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), identified in late 2019 as the causative agent of COVID-19, was declared a pandemic by the World Health Organization on 11 March 2020. Widespread community transmission in the United States triggered a nationwide shutdown, raising major challenges for administration of hematopoietic stem cell transplant (HSCT) and chimeric antigen receptor (CAR)-T cell therapies, leading many centers to delay or cancel operations. We sought to assess the impact of the COVID-19 pandemic on operations and clinical outcomes for HSCT and CAR-T cellular therapies at the Dana-Farber Cancer Institute by reviewing administration and outcomes in 127 cell therapy patients treated during the initial COVID-19 surge: 62 adult allogeneic HSCT (allo-HSCT), 38 autologous HSCT (auto-HSCT), and 27 CAR-T patients.

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Purpose: This study evaluated the ability of topographically correspondent (TC) minimum rim width (MRW) and peripapillary retinal nerve fiber layer thickness (pRNFLT) criteria to detect optical coherence tomography (OCT) structural abnormality in glaucoma (GL) and glaucoma suspect (GLS) eyes.

Design: Retrospective cross-sectional study.

Methods: A total of 196 GL eyes, 150 GLS eyes, and 303 heathy eyes underwent pRNFL and 24 radial optic nerve head OCT imaging and manual correction of the internal limiting membrane, Bruch's membrane opening (BMO), and outer pRNFL segmentations.

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