Publications by authors named "Cinderella Wai-Shan Chung"
Article Synopsis
- Bufalin, a key compound from Chan-Su, was studied for its effects on SK-HEP-1 human liver cancer cells, finding that it inhibits cell survival and increases cell death in a dose-dependent manner.
- The research revealed that bufalin causes G2/M phase cell cycle arrest by lowering CDK1 activity and induces both apoptotic and autophagic cell death through various mechanisms, including DNA damage and changes in protein expression.
- Overall, bufalin may serve as a promising treatment option for human hepatocellular carcinoma by affecting critical cellular pathways like AKT/mTOR.
