Gastroprotective effect and mechanism of action of Croton rhamnifolioides essential oil in mice.

Background: Croton rhamnifolioides Pax is a plant species that have been used in the folk medicine to treat ulcers, inflammations and hypertension. However, despite the relevant data obtained from ethnopharmacological studies, the pharmacological properties endorsing the efficacy of this plant to treat ulcer remain to be elucidated.

Hypothesis/purpose: The present study aimed to characterize the chemical profile and evaluate the gastroprotective activity of the essential oil obtained from C.