The study investigates the impact of acromegaly on retinal vascular health and its link to Gremlin-1 levels using optical coherence tomography angiography (OCTA).
It involved 53 acromegaly patients and 31 healthy controls, measuring retinal structures and Gremlin-1 concentrations through elaborate imaging and blood tests.
Results indicated that acromegaly patients exhibited significantly reduced retinal vascular densities and lower Gremlin-1 levels compared to controls, suggesting a negative association between acromegaly and vascular health independent of glucose tolerance.