Publications by authors named "Cigdem Caglayan"

Nowadays, self-healing materials have been studied actively in electronics, soft robotics, aerospace, and automobiles because they can prolong the life span of the materials. However, overcoming the trade-off relationship between mechanical properties and self-healing performance is challenging. Herein, graphene oxide-polyaniline (GO-PANI) filler was introduced to overcome this challenge because GO has a highly excellent modulus, and nitrogen atoms in PANI can endow a self-healing ability through hydrogen bonds.

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Objectives: This study aims to present an overview of the formal recognition of COVID-19 as occupational disease (OD) or injury (OI) across Europe.

Methods: A COVID-19 questionnaire was designed by a task group within COST-funded OMEGA-NET and sent to occupational health experts of 37 countries in WHO European region, with a last update in April 2022.

Results: The questionnaire was filled out by experts from 35 countries.

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Introduction: Coronavirus disease 2019 (COVID-19) infection was declared a pandemic, causing high mortality and morbidity worldwide. It predisposes patients to both arterial and venous thromboembolism, which causes high mortality, and is one of the most serious complications of the disease.

Objective: The aim of this retrospective study was to determine the frequency of thromboembolic events in patients diagnosed with COVID-19 in the intensive care unit (ICU) and to identify the factors causing thromboembolism.

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Article Synopsis
  • Physician immigration to developed countries is on the rise, but the reasons behind Turkish physicians' migration are still not well understood.
  • A study of 9,881 senior medical students in Türkiye showed that 70.7% intend to emigrate, with about 60% wanting to stay abroad permanently.
  • The main factors influencing their decisions include poor working conditions in Türkiye and a desirable social environment abroad, along with concerns about medical school quality significantly impacting their emigration intentions.
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In this paper, catalyst-free room-temperature healing epoxy vitrimer-like materials (S-vitrimer) are introduced. The S-vitrimer can be healed at room temperature without any external stimuli such as solvent, pressure, heat, and catalyst through an aromatic disulfide exchange reaction and a hydrogen bond because the glass transition temperature of the S-vitrimer is lower than room temperature. Self-healing materials are attracting widespread attention nowadays with their potential to increase the durability of the materials.

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The design and utilization of polymers with healing capability have drawn increasing attention owing to their enhanced chain mobility and opportunity to heal minor cracks in composites. Rehealable thermoset polymers promise reduction in the maintenance cost and thus prolonged lifetime, reshaping, and recyclability. Introducing reversible covalent bonds is the mainstay strategy to achieve such plasticity in crosslinked polymers.

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We aimed to review the determinants of burnout onset in teachers. The study was conducted according to the PROSPERO protocol CRD42018105901, with a focus on teachers. We performed a literature search from 1990 to 2021 in three databases: MEDLINE, PsycINFO, and Embase.

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Article Synopsis
  • A mathematical model was used to predict the future prevalence of type 2 diabetes mellitus (T2DM) and associated risk factors like obesity, physical inactivity, and smoking in Turkey, focusing on trends up to 2050.
  • The model analyzed demographic data from 1997 to 2017 and explored different scenarios regarding obesity rates, particularly forecasting a potential decline in obesity among women.
  • The findings suggest a rising T2DM prevalence in Turkey, especially among women, highlighting the need for targeted interventions to address obesity and improve physical activity to mitigate future health burdens.
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We aimed to review occupational burnout predictors, considering their type, effect size and role (protective versus harmful), and the overall evidence of their importance. MEDLINE, PsycINFO, and Embase were searched from January 1990 to August 2018 for longitudinal studies examining any predictor of occupational burnout among workers. We arranged predictors in four families and 13 subfamilies of homogenous constructs.

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Objective A consensual definition of occupational burnout is currently lacking. We aimed to harmonize the definition of occupational burnout as a health outcome in medical research and reach a consensus on this definition within the Network on the Coordination and Harmonisation of European Occupational Cohorts (OMEGA-NET). Methods First, we performed a systematic review in MEDLINE, PsycINFO and Embase (January 1990 to August 2018) and a semantic analysis of the available definitions.

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Background: The lack of 6-year follow-up studies that test the effect of recreational activities in the recovery of social phobia and shyness symptoms is the reason to conduct this study.

Aim: The purpose is to follow the effect of the 12-week recreational activity program found to eliminate social phobia and shyness symptoms after the completion of university studies in its sixth year.

Methods: At the end of the 12-week recreational activity program that treats the symptoms of social phobia and shyness in university prep school students, 83 students who participated in the posttest both from intervention and control groups were invited to the study.

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Objectives The aims of this position paper are to (i) summarize research on precarious employment (PE) in the context of occupational health; (ii) develop a theoretical framework that distinguishes PE from related concepts and delineates important contextual factors; and (iii) identify key methodological challenges and directions for future research on PE and health. Methods This position paper is the result of a working group consisting of researchers from the EU, Turkey and the USA, who have discussed the issue over the course of six months (October 2018-April 2019), meeting both online and face-to-face on several occasions. Results The lack of a common theoretical framework of PE hinders it from becoming an established part of occupational and public health research.

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Background: Classic Kaposi sarcoma usually remains on the skin and has a slow progression; thus, local treatment methods are preferable. Imiquimod is an immunomodulatory agent with antiviral, antitumoural, and antiangiogenic properties that is expedient against Kaposi sarcoma.

Objectives: We aimed to clarify whether imiquimod is effective on classic Kaposi sarcoma lesions by comparing imiquimod treatment with cryotherapy, which is the most-used treatment method in our department for this disease.

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Article Synopsis
  • * Among 1499 patients studied, significant mortality rates were found in those with severe sepsis (55.7%) and septic shock (70.4%), and respiratory infections were the most common, specifically caused by Acinetobacter spp.
  • * The study highlighted high levels of antibiotic resistance, with 74.9% of Acinetobacter isolates resistant to carbapenems; however, resistance did not correlate with increased mortality.
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Introduction: In this study, we aimed to determine the changes in quality of life of children/adolescents with anxiety disorders during six months of sertraline treatment, to investigate parent-child/adolescent concordance in perception of quality of life and to examine the effect of treatment on children/adolescents.

Methods: In this study, 30 patients with anxiety disorders according to criteria specified in Diagnostic and Statistical Manual of Mental Disorders, 4. Edition (DSM-IV) were assigned to sertraline treatment.

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Background: Nails, one of the most visible sites of body, are frequently involved in psoriasis and accepted as the most difficult site for topical treatment because of their anatomical structure. Healing of the psoriatic nails usually occurs when systemic therapy is initiated to treat severe skin psoriasis or joint involvement, but sometimes systemic therapy is essential for severe nail psoriasis, although Psoriasis Area and Severity Index (PASI) score is low or none of the joints are affected. In this case, knowing which systemic agent is most potent on nail findings is important.

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Background: In uremic patients, depending on their type, the T-cells produce a range of pro-inflammatory and anti-inflammatory cytokines. The aim of this study was to compare the effects of chronic kidney disease (CKD) and two different therapy methods of dialysis [hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD)] on adiponectin, TNF-alpha, and hs-CRP levels in human serum.

Methods: We measured the serum levels of hs-CRP, adiponectin, and TNF-alpha in 37 patients with CKD on conservative treatment, 34 patients maintained on CAPD, 35 HD patients, and 25 healthy volunteers.

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Background: Inflammatory bowel disease (IBD) patients have an increased risk for thromboembolism. The aim of this study was to assess the presence of thrombophilic risk factors in IBD patients and to assess the associations of these factors with disease activity.

Methods: Forty-eight patients with IBD (24 ulcerative colitis, 24 Crohn's disease) and 40 matched healthy control individuals were enrolled.

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Deaths and injuries linked to traffic accidents are important public health issues. In this descriptive study, the accidents resulting in death and injury between 2000 and 2004 on the city portion of the D-100 were compared with those on the other roads within the city. The D-100 had a fatality risk approximately 2 times higher than that of the other roads within the city.

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Objectives: We studied the influence of patient positioning on the visibility of the sciatic nerve during ultrasound (US) examination in the popliteal region.

Methods: Using a linear broad band 7-12 MHz frequency probe, US examination of 24 sciatic nerves was performed by a blinded operator to obtain the best possible image at the level of the popliteal crease (PC) and at 4 and 8 cm above the PC in the prone position. Examinations were performed in neutral prone (Group N), with a silicone roller under the foot (Group R) and in "figure of four" (Group FOF) positions.

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Background: Child labor remains a widespread phenomenon in today's world. The purpose of the present study was to describe the working conditions and health status of child workers in Kocaeli.

Methods: A cross-sectional research study has been carried out on 365 working children at the Kocaeli Occupational Training Center.

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Background/aims: A close relationship exists between inflammation and vascular calcification. Although fetuin-A is known to be an inhibitor of calcification, studies correlating levels of this glycoprotein to markers of inflammation are limited. To understand these relationships, we investigated the relationship between serum fetuin-A and proinflammatory cytokine levels in patients with chronic renal failure (CRF).

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Background: Serum levels of adipocytokines such as leptin and adiponectin are significantly elevated in patients with chronic renal failure (CRF). The effect of such adipocytokines on malnutrition in the CRF population has been of substantial interest. We sought to determine the relationship between plasma leptin and adiponectin levels and malnutrition-inflammation status in end-stage renal disease patients.

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Background/aims: Cytokine secretion is known to play an important role in the pathophysiology of depression, and levels of proinflammatory cytokines are increased in chronic renal failure (CRF) patients. The objective of this study was to examine the correlation between levels of proinflammatory cytokines in CRF patients and degree of depression.

Methods: 31 patients on hemodialysis, 31 patients on continuous ambulatory peritoneal dialysis, and 31 conservatively managed chronic kidney disease (CKD) patients were enrolled in this study.

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