Potentiation of the Activity of Antibiotics against ATCC and MDR Bacterial Strains with (+)--Pinene and (-)-Borneol.

The increasing rates of antimicrobial resistance have demanded the development of new drugs as conventional antibiotics have become significantly less effective. Evidence has identified a variety of phytocompounds with the potential to be used in the combat of infections caused by multidrug-resistant (MDR) bacteria. Considering the verification that terpenes are promising antibacterial compounds, the present research aimed to evaluate the antibacterial and antibiotic-modulating activity of (+)--pinene and (-)-borneol against MDR bacterial strains.

Antibiotic potentiating action of α-PINENE and borneol against EPEC and ETEC sorotypes.

Escherichia coli is considered the main cause of intestinal and extra-intestinal infections, they have virulence mechanisms in different pathotypes and the ability to receive or transmit antimicrobial resistance genes. The aim of this work was to investigate the antibacterial and antimicrobial modulating activity of α-pinene and borneol against E. coli and enteropathogenic (EPEC) and enterotoxigenic (ETEC) serotypes.