XbaI polymorphism in the APOB gene and its association with increased cholesterol in children and adolescents: Ouro Preto study.

Atherosclerotic vascular changes can begin during childhood, providing risk for cardiovascular disease (CVD) in adulthood. Identifiable risk factors such as dyslipidemia accelerate this process for some children. The apolipoprotein B (APOB) gene could help explain the inter-individual variability in lipid levels among young individuals and identify groups that require greater attention to prevent CVD.

Evaluation of the prevalence and factors associated with acute kidney injury in a pediatric intensive care unit.

Objective: To assess the prevalence of acute kidney injury in pediatric intensive care unit according to diagnostic criteria - pediatric risk, injury, failure, loss, end-stage renal disease, Acute Kidney Injury Network and Acute Kidney Injury Work Group, or Kidney Disease: Improving Global Outcomes -, and determining factors associated with acute kidney injury as well as its outcome.

Methodology: This was a cross-sectional monocentric observational study, including patients aged between 29 days and 17 years who were admitted to the pediatric intensive care unit between January 1, 2012 and December 31, 2016. To evaluate the association between the study variables and acute kidney injury, the log-binomial generalized univariate and multivariate linear models were adjusted.

A Sensor for Spirometric Feedback in Ventilation Maneuvers during Cardiopulmonary Resuscitation Training.

This work proposes adapting an existing sensor and embedding it on mannequins used in cardiopulmonary resuscitation (CPR) training to accurately measure the amount of air supplied to the lungs during ventilation. Mathematical modeling, calibration, and validation of the sensor along with metrology, statistical inference, and spirometry techniques were used as a base for aquiring scientific knowledge of the system. The system directly measures the variable of interest (air volume) and refers to spirometric techniques in the elaboration of its model.