Publications by authors named "Chyi-Huey Bai"

Purpose: Vitamin D supplementation positively impacts anemia, but the relationship between a ferritin-related dietary pattern, iron parameters, and vitamin D in anemia is unclear.

Methods: This cross-sectional study analyzed data from the 2017-2019 National Nutrition and Health Survey, including 1423 pregnant women over 15 years old. Dietary intake was assessed using a semi-quantitative food frequency questionnaire and a 24-hour dietary recall.

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Background: In Taiwan's public health system, community-based pharmacists are key first-line health care providers due to their high accessibility. During the COVID-19 pandemic, the pharmacists played a central role in the distribution of these supplies through the Name-Based Rationing System (NBRS), during an acute shortage of masks and testing kits, that helped reduce the spread of the disease. The NBRS, an innovative government-guided strategy developed after the COVID-19 outbreak, provided equitable and convenient access to masks and COVID-19 test kits.

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Unwanted pregnancies resulting in detrimental consequences for both the mother and the child, including low birth weight, pose a remarkable challenge in developing countries. Although the association between low birth weight (LBW) and unwanted pregnancy is widely demonstrated, the results have been inconsistent, and the underlying mechanisms remain unclear. We examined maternal antenatal care (ANC) completeness as a potential mediating factor of the association between unwanted pregnancy and LBW among women in Indonesia, as well as the moderating effect of family support during pregnancy.

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  • Lung cancer is the top cause of cancer deaths globally, and screening high-risk individuals with low-dose CT scans can help reduce mortality.
  • This meta-analysis investigated the effectiveness of rapid on-site evaluation (ROSE) during bronchoscopy for improving diagnostic accuracy in lung cancer detection using data from 32 studies with over 8,200 lung lesions.
  • The findings showed that ROSE has high sensitivity (91.8%) and specificity (94.9%) for lung cancer diagnosis, particularly in patients who had low-dose CT scans, and it is also effective for staging lung cancer with endobronchial ultrasound-guided needle aspiration.
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  • The study explores how dietary glycemic index (GI) and glycemic load (GL) influence changes in glycemic control and cardio-metabolic health over 28 months in 110 Vietnamese diabetic patients.
  • Findings revealed three different HbA1c patterns, with 51% of participants maintaining good glycemic control during the study.
  • An increase in dietary GL was linked to higher HbA1c levels, particularly in patients with poor glycemic control, while GI impacted fasting plasma glucose and triglyceride-glucose index, showing no significant effects in those with good control.
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  • Hyperlipidemia is linked to coronary artery disease (CAD) and the proinflammatory cytokine IL-18 plays a role in its development; this study focuses on the connection between IL-18 genetic variations and hyperlipidemia in the Han Chinese population in Taiwan.
  • The research analyzed 580 community participants over 30 years old, collecting data on demographics, health histories, and lipid profiles, while investigating two specific IL-18 single nucleotide polymorphisms (SNPs) related to cholesterol levels.
  • Findings indicated that specific SNPs in IL-18 (rs3882891 and rs1946518) were associated with cholesterol levels and hypercholesterolemia risk, with the AC haplotype showing a
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  • - This study explores the effects of comorbidities on the relapse rates of patients with Neuromyelitis optica spectrum disorder (NMOSD) in Taiwan, based on data collected from 485 patients over 15 years.
  • - The results showed that the median annualized relapse rates (ARR) were similar for adult and pediatric patients and that common comorbidities like malignancy and autoimmune diseases did not significantly affect ARR in the first three years post-diagnosis.
  • - The researchers found a notably higher risk of malignancy in adult NMOSD patients compared to the general population, suggesting the need for further investigation into how these two conditions may be related.
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  • The text indicates that there is a correction to a previously published article.
  • The DOI (Digital Object Identifier) provided, 10.1371/journal.pone.0252844, refers to the specific article that is being corrected.
  • This correction is an important part of academic publishing, ensuring that the information presented is accurate and reliable.
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A systematic review and meta-analysis was conducted to evaluate the relative effectiveness of different dietary macronutrient patterns on changes in resting energy expenditure (REE) in relation to weight loss, categorized as minimal (<5%) and moderate to high (>5%). Changes in REE were assessed using a DerSimonian and Laird random-effects meta-analysis. A diet lower in carbohydrates (CHO) or higher in fat and protein was associated with smaller reductions in REE, with these trends being more pronounced among participants who experienced moderate to high weight loss.

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Background And Aims: The present study aimed to investigate the predictive ability of selected adiposity indices, such as body mass index (BMI), waist-to-hip ratio (WHR), waist circumference (WC), and waist-to-height ratio (WHtR), for new-onset hypertension in metabolically healthy Taiwanese adults. The study also sought to establish sex-specific cutoff points for these indices and to analyze the risk of new-onset hypertension, taking into account sex and age.

Methods: This prospective cohort study utilized the Taiwan Biobank database to examine metabolically healthy participants aged between 20 and 65 at baseline.

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Ischemic stroke, the most prevalent form of stroke, leads to neurological impairment due to cerebral ischemia and affects 55-90% of the population. Brain-derived neurotrophic factor (BDNF) plays a crucial role in the central nervous system and regulates cardiometabolic risk factors, including lipids. This single-center study aimed to explore the relationship between lipid profiles and BDNF levels in 90 patients who had experienced AIS for the first time.

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This paper reviewed the most effective strategies for preventing work absence due to back pain (BP) and BP episodes (the number of people reporting back pain). We searched randomized controlled trials (RCTs) of prevention strategies for BP from previous meta-analyses, PubMed, CENTRAL, and Embase and conducted a network meta-analysis. Thirteen RCTs (2033 participants) were included.

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Background: Sugar-sweetened beverages (SSBs) are the main cause of excessive sugar intake and increased health risks. Food companies usually use social media to market SSBs in order to increase consumers' purchase intentions. To reduce excessive added sugar consumption from hand-shaken tea drinks, Taiwan has implemented a mandatory policy requiring clear sugar content labeling.

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Background: Tirofiban is an antiplatelet treatment approved for acute coronary syndrome, but it has not been rigorously evaluated for efficacy and safety in patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT).

Methods: Electronic databases were systematically searched for studies conducted from January 1, 2015, to July 31, 2021, that evaluated tirofiban administration for patients with AIS treated with EVT in comparison with control. Risk ratios (RRs) and confidence intervals (CIs) were estimated for favorable functional outcomes (FFOs), mortality, and symptomatic intracranial hemorrhage (SICH), each 90 days after AIS.

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Background: Continuous positive airway pressure (CPAP) therapy is the first-line treatment for obstructive sleep apnea (OSA). However, the low acceptance rate of CPAP remains a challenging clinical issue. This study aimed to determine the factors that influence the acceptance rate of CPAP.

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  • The study evaluated the effectiveness and safety of sodium-glucose cotransporter 2 inhibitors (SGLT2is) specifically in patients with chronic kidney disease (CKD), as previous reviews had not focused on this group.
  • A systematic review and meta-analysis were conducted, reviewing 30 studies, which found that SGLT2is led to a slower decline in kidney function (measured by eGFR) and significantly improved urine albumin-to-creatinine ratios in CKD patients.
  • While SGLT2is showed potential benefits for kidney health in CKD patients, particularly those with high levels of albuminuria or advanced CKD, there was a slight increase in risks for certain adverse effects like genital infections
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Background: Real-time and appropriate antigen tests play a pivotal role in preventing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. However, a previous meta-analysis reported that the antigen test had lower sensitivity for the detection of SARS-CoV-2 in children. To provide a comprehensive evaluation of diagnostic efficiency, we performed an updated meta-analysis to assess the detection accuracy of SARS-CoV-2 antigen tests stratified by days after symptom onset and specimen type in children and adolescents.

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  • The study investigates the relationship between two methods for measuring liver fat—Controlled Attenuation Parameter (CAP) and Fatty Liver Index (FLI)—and their effectiveness in identifying early stages of metabolic syndrome (MetS).
  • Using data from 170 individuals, the study calculates the odds of being in higher MetS stages based on CAP and FLI scores, finding that higher scores correlate with a greater likelihood of MetS.
  • FLI showed a better ability to distinguish between stages of MetS compared to CAP, particularly in identifying mild to severe cases, indicating both methods could be viable for community MetS screening.
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Brain-derived neurotrophic factor (BDNF) interacts with tropomyosin-related kinase B (TrkB) to promote neuronal growth, survival, differentiation, neurotransmitter release, and synaptic plasticity. The translocator protein (TSPO) is known to be found in arterial plaques, which are a symptom of atherosclerosis and a contributory cause of ischemic stroke. This study aims to determine the diagnostic accuracy of plasma BDNF and TSPO levels in discriminating new-onset acute ischemic stroke (AIS) patients from individuals without acute ischemic stroke.

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Background: Benzene, toluene, ethylbenzene, and xylenes, collectively known as BTEX, are hazardous chemical mixtures, and their neurological health effects have not been thoroughly evaluated. We examined the association between BTEX exposure and neurological hospital admissions.

Methods: This was a multicity time-series study conducted in five major Taiwanese cities.

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Globally, anemia affects 56 million pregnant women, especially women with a low household income. Functional erythropoiesis requires a constant supply of micronutrients, and the demands significantly increase during fetal development. This study aims to identify dietary patterns for preventing gestational erythropoiesis-associated micronutrient deficiencies (e.

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Vitamin D is involved in the pathophysiology of anemia. This cross-sectional study was conducted using the Nationwide Nutrition and Health Survey in Pregnant Women in Taiwan database. We investigated associations among dietary patterns (DPs), vitamin D, and iron-related biomarkers in pregnant women.

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Introduction: This study looked into the effectiveness of a 6 month health coaching intervention in smoking cessation and smoking reduction for patients with type 2 diabetes.

Methods: The study was carried out via a two-armed, double-blind, randomized-controlled trial with 68 participants at a medical center in Taiwan. The intervention group received health coaching for 6 months, while the control group only received usual smoking cessation services; some patients in both groups participated in a pharmacotherapy plan.

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Background: Vitamin D deficiency (VDD) is a global micronutrient issue that commonly occurs in pregnant women, leading to adverse health outcomes. We examined the role of sunlight-related factors and dietary vitamin D intake on vitamin D concentrations among pregnant women in different climate zones.

Methods: We conducted a nationwide cross-sectional survey in Taiwan between June 2017 and February 2019.

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