Ultrasound-Assisted H Transmitter Enables Hydrogen-Gene Therapy to Prevent Anesthesia/Surgery-Induced Cognitive Impairment.

Postoperative cognitive dysfunction (POCD) frequently occurs after surgery, resulting in extended hospitalizations, higher healthcare expenses, and potential long-term cognitive impairment. Despite its significant impact, effective preventive and therapeutic strategies for POCD are still lacking. Neuroinflammation plays a crucial role in the pathogenesis of POCD.