Publications by authors named "Chuyue Huang"
The liver is a major metabolic organ of the human body and has a high incidence of diseases. In recent years, the annual incidence of liver disease has increased, seriously endangering human life and health. The study of the occurrence and development mechanism of liver diseases, discovery of new therapeutic targets, and establishment of new methods of medical treatment are major issues related to the national economy and people's livelihood.
View Article and Find Full Text PDFBackground: Banxia Xiexin decoction (BXD) is a traditional Chinese medicine with anti-colorectal cancer (CRC) activity. However, its bioactive constituents and its mechanism of action remain unclear. Herein, we explored the mechanism of action of BXD against CRC using a network pharmacology approach.
View Article and Find Full Text PDFLiquiritin is a natural flavone with a variety of pharmacological effects derived from the medicinal food homology plant h. As a kind of lethal allergic reactions, pseudo-allergic reactions (PARs) arise from the Mas-related G protein coupled receptor X2 (MRGPRX2)-triggered fast degranulation of mast cells (MCs). In the current work, the anti-pseudo-allergy action and potential mechanisms of liquiritin were explored and .
View Article and Find Full Text PDFArticle Synopsis
- A new method called RR-BART is introduced to improve variable selection in datasets with missing values, particularly when the missing data is missing at random (MAR).
- RR-BART uses a combination of Bayesian machine learning and Rubin's rule to effectively handle data imputation and variable importance evaluation, outperforming traditional bootstrap methods.
- Simulation studies and a real case study reveal that RR-BART can detect important predictors more efficiently, including those that are often overlooked, while saving on computational resources.