Publications by authors named "Chuyuan Ni"
Predicting symptomatic intracranial hemorrhage after endovascular treatment of vertebrobasilar artery occlusion: PEACE score.
J Neurointerv Surg
February 2025
Background: Current clinical decision tools for assessing the risk of symptomatic intracranial hemorrhage (sICH) in patients with vertebrobasilar artery occlusion (VBAO) who received endovascular treatment (EVT) have limited performance. This study develops and validates a clinical risk score to precisely estimate the risk of sICH in VBAO patients.
Methods: The derivation cohort recruited patients with VBAO who received EVT from the Posterior Circulation IschemIc Stroke Registry in China.
Objective: To assess whether intra-arterial tenecteplase administered after successful endovascular recanalisation improves outcomes in patients with acute arterial occlusion of the posterior circulation.
Design: Multicentre randomised controlled trial.
Setting: 31 hospitals in China, 24 January 2023 to 24 August 2023.
Article Synopsis
- Patients with large vessel occlusion (LVO) stroke who are transferred to comprehensive stroke centers often face increased infarct growth, which can negatively impact their outcomes after treatment.
- A study was conducted on 309 patients to analyze factors affecting the rate of infarct growth during transfer, using measurements like the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) decay.
- Results showed that fast infarct growth correlates with worse 90-day outcomes and is linked to higher stroke severity scores at admission, proximal occlusions, and poor collateral blood circulation, while prior intravenous thrombolysis did not positively influence infarct growth during transfer.
Article Synopsis
- Malignant cerebral edema (MCE) occurs in 13.2% of patients with acute basilar artery occlusion (BAO) receiving endovascular treatment (EVT), which is crucial as MCE can lead to severe functional impairment and increased mortality.
- Predictors for developing MCE include a lower Glasgow Coma Scale (GCS) score and a higher number of medical procedures, indicating that initial patient condition and treatment intensity are important factors.
- MCE is linked to significantly worse clinical outcomes, resulting in lower rates of functional independence and higher mortality rates after 90 days, highlighting the need for improved management strategies.
Background And Purposes: Ischemic stroke caused by acute internal carotid artery occlusions (AICO) is usually associated with high disability and mortality. We aimed to investigate whether occlusion patterns significantly influence clinical outcome in patients receiving endovascular thrombectomy (EVT).
Patients And Methods: We performed a retrospective analysis of databases from two comprehensive stroke centers and consecutively investigated patients who had underwent EVT.
Background: The authors compare the effectiveness and safety of endovascular treatment (EVT) versus best medical management (BMM) in strokes attributable to acute basilar artery occlusion (BAO).
Methods: The present analysis was based on the ongoing, prospective, multicenter ATTENTION (Endovascular Treatment for Acute Basilar Artery Occlusion) trial registry in China. Our analytic sample comprised 2134 patients recruited at 48 sites between 2017 and 2021 and included 462 patients who received BMM and 1672 patients who received EVT.