Bacteria-responsive drug release platform for the local treatment of bacterial vaginosis.

Bacterial vaginosis (BV) is a common vaginal infection affecting millions of women. Vaginal anaerobic dysbiosis occurs whenspp., the dominant flora in healthy vagina is replaced by certain overgrown anaerobes, resulting in unpleasant symptoms such as vaginal discharge and odor.

Desertibaculum subflavum gen. nov., sp. nov., a novel member of the family Sneathiellaceae isolated from the Kumtag Desert soil.

A novel rod-shaped bacterium, designated as strain SYSU D60015 that formed yellowish colonies was isolated from a sandy soil collected from the Kumtag Desert in Xinjiang, China. Cells were Gram-stain-negative, oxidase-positive, catalase-negative and motile with a single polar flagellum. Growth optimum occurred between 28 and 37 °C, pH 7.

gen. nov., sp. nov. and sp. nov., isolated from desert soil.

Two Gram-stain-negative, aerobic, milk-white coloured, non-motile, short rod-shaped bacteria, designated as strains SYSU D60010 and SYSU D60012, were isolated from sand samples collected from the Taklimakan Desert of Xinjiang Province in China. Both strains were positive for oxidase, catalase and nitrate reduction, but negative for amylase, HS production, hydrolysis of gelatin and cellulase. Strains SYSU D60010 and SYSU D60012 grew well at 28 °C, at pH 7 and had the same NaCl tolerance range of 0-1 % (w/v).

Telluribacter roseus sp. nov., Isolated from the Kumtag Desert Soil.

A pink-pigmented bacterium, designated as strain SYSU D00476, was isolated from sandy soil collected from the Kumtag Desert in China. Colonies were opaque, smooth and of a slight convexity with a clearly defined border. Cells were rod-shaped, Gram-stain-negative, catalase- and oxidase-positive.

sp. nov., isolated from desert soil.

Two Gram-stain-negative strains, designated as SYSU D00286 and SYSU D00782, were isolated from a sand sample collected from the Kumtag Desert in Xinjiang, north-west China. Cells were aerobic, non-motile and positive for both oxidase and catalase. Growth occurred at 4-37 °C (optimum, 28-30 °C), pH 6.

Doxorubicin nanoformulations on therapy against cancer: An overview from the last 10 years.

Doxorubicin (DOX) is a natural antibiotic with antineoplastic activity. It has been used for over 40 years and remains one of the most used drugs in chemotherapy for a variety of cancers. However, cardiotoxicity limits its use for long periods.

Conjugated Polymer Nanoparticles Based Fluorescent Electronic Nose for the Identification of Volatile Compounds.

A fluorescence sensing array (or fluorescent electronic nose) is designed on a disposable paper card using 36 sets of soluble conjugated polymeric nanoparticles (SCPNs) as sensors to easily identify wide ranges of volatile analytes, including explosives and toxic industrial chemicals (amines and pungent acids). A 108-dimensional vector obtained from the fluorescent color change in the sensing array is defined and directly treated as an index in a standard chemical library (30 kinds of volatile analytes and a control group). Hierarchical clustering analysis (HCA) and principal component analysis (PCA) indicated the diversity in electronic structures; saturated vapor pressure and miscibility of analytes are keys in differentiating the analytes, with electron-rich arenes and alkylamines enhancing fluorescence and electron-deficient analytes attenuating fluorescence.