Alcoholic liver disease (ALD) denotes a series of liver diseases caused by ethanol. Recently, immune-related genes (IRGs) play increasingly crucial role in diseases. However, it's unclear the role of IRGs in ALD.
View Article and Find Full Text PDFAlcoholic liver disease (ALD) is one of the most common chronic liver diseases worldwide. However, the potential molecular mechanism in ALD development remains unclear. The objective of this work was to identify key molecules and demonstrate the underlying regulatory mechanisms.
View Article and Find Full Text PDFBackground: Long non-coding RNAs (lncRNAs) are often aberrantly expressed in hepatocellular carcinoma (HCC). The role of lncRNAs in the diagnosis of HCC has attracted increasing attention. Hence, we performed a meta-analysis based on current studies to assess the diagnostic value of lncRNAs for HCC.
View Article and Find Full Text PDFCervical squamous cell carcinoma (CESC) is one of the most frequent malignancies in women worldwide. The level of immune cell infiltration and immune-related genes (IRGs) can significantly affect the prognosis and immunotherapy of CESC patients. Thus, this study aimed to identify an immune-related prognostic signature for CESC.
View Article and Find Full Text PDFThe thermal and ionic effects on the phase transitions of poly(N-isopropylacrylamide) (PNIPAAm) and its copolymer with benzo-18-crown-6-acrylamide, poly(N-isopropylacrylamide-co-benzo-18-crown-6-acrylamide) (PNIPAAm-co-BCAm), were investigated using infrared (IR) spectral variations of methyl (CH3), C=O, and amine (NH) groups. Subsequently, perturbation correlation moving-window two-dimensional correlation infrared spectroscopy (PCMW 2D-IR) was applied to clarify the differences in the phase-transition mechanisms of the polymers. The dominant influence on the phase-transition mechanism of PNIPAAm is whether the anion is evenly distributed in the bulk solution.
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