Publications by authors named "Chuye Mo"
Article Synopsis
- - This study aimed to clarify the relationship between circulating micronutrient levels and the risk of systemic lupus erythematosus (SLE) by using two-sample Mendelian randomization analysis, focusing on 14 specific micronutrients.
- - Researchers utilized 56 SNPs as instrumental variables to analyze how micronutrient levels might influence SLE risk, employing various statistical methods for robustness, including the MR Steiger test and logistic regression analyses.
- - The findings indicated that lower levels of calcium and iron were correlated with a reduced risk of SLE, as confirmed by both the Mendelian randomization approach and retrospective analysis of participants from the NHANES III database.
Background: Previous studies have shown the association between tuberculosis (TB) and meteorological factors/air pollutants. However, little information is available for people living with HIV/AIDS (PLWHA), who are highly susceptible to TB.
Method: Data regarding TB cases in PLWHA from 2014 to2020 were collected from the HIV antiviral therapy cohort in Guangxi, China.
Background: Growing evidence from observational studies and clinical trials suggests that the gut microbiota is associated with tuberculosis (TB). However, it is unclear whether any causal relationship exists between them and whether causality is bidirectional.
Methods: A bidirectional two-sample Mendelian randomization (MR) analysis was performed.
Background: Cardiovascular diseases (CVD) and type 2 diabetes (T2D) account for the majority of the burden of noncommunicable disease caused by low physical activity (LPA). In order to inform future interventions, this study aims to assess the burden and trends in mortality and disability-adjusted life years (DALYs) of CVD and T2D attributable to LPA by year, location, sex, and age from 1990 to 2019.
Methods: Mortality, DALYs, and their age-standardised rates (ASMR, ASDR) for CVD and T2D attributable to LPA were retrieved from Global Burden of Disease (GBD) 2019.
Chronic inflammation is recognized as a major risk factor for the severity of HIV infection. Whether metabolism reprogramming of macrophages caused by HIV-1 is related to chronic inflammatory activation, especially M1 polarization of macrophages, is inconclusive. Here, we show that HIV-1 infection induces M1 polarization and enhanced glycolysis in macrophages.
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