Publications by authors named "Chuxin Lin"
Background: This study aims to evaluate the ability of laboratories to perform spinal muscular atrophy (SMA) genetic testing in newborns based on dried blood spot (DBS) samples, and to provide reference data and advance preparation for establishing the pilot external quality assessment (EQA) scheme for SMA genetic testing of newborns in China.
Methods: The pilot EQA scheme contents and evaluation principles of this project were designed by National Center for Clinical Laboratories (NCCL), National Health Commission. Two surveys were carried out in 2022, and 5 batches of blood spots were submitted to the participating laboratory each time.
Article Synopsis
- The study investigates how using multiple b-values in Diffusion-weighted imaging (DWI) improves imaging quality and diagnostic accuracy for breast lesions compared to conventional methods.
- It involves 41 patients with benign tumors and 38 with malignant tumors, analyzing various parameters to determine their diagnostic performance using statistical methods.
- The findings suggest that a specific multiparametric combination (ADC-ADC) provides the best results for distinguishing between benign and malignant breast lesions, with notable sensitivity and specificity outcomes.
Solitary fibrous tumors (SFTs) are commonly seen in the pleura. SFT involvement of the vulva is rare, and clinical diagnosis is mainly based on histopathological and immunohistochemical analyses. We herein describe the imaging features of a 69-year-old woman with an SFT of the vulva.
View Article and Find Full Text PDFAn Oxygen-Enriched Photodynamic Nanospray for Postsurgical Tumor Regression.
ACS Biomater Sci Eng
November 2020
Article Synopsis
- Postoperative recurrence and metastasis are major challenges in cancer treatment, but photodynamic therapy (PDT) shows promise due to its targeted and non-invasive nature.
- Conventional PDT often struggles with low oxygen levels, limiting its effectiveness, which prompted the development of a new oxygen-enriched nanospray using liposomes combined with indocyanine green (ICG) and perfluorooctyl bromide (PFOB).
- This new treatment, Lip-PFOB-ICG, enhances the PDT effect under near-infrared light by improving oxygen absorption, leading to significant inhibition of local tumor recurrence and potentially offering a better postoperative therapy option.