Spontaneous Hemothorax by Pulmonary Arteriovenous Malformation during Pregnancy.

 Pulmonary arteriovenous malformation (PAVM) is a rare vascular malformation that may cause hemothorax, especially during pregnancy.  A 25-year-old woman presented sudden-onset left chest pain, dizziness, and dyspnea in the 27th week of gestation. Computed tomography angiography showed left pleural effusion with complete hemithorax opacification and an aneurysmal PAVM.

MicroRNA-137-regulated AKT serine/threonine kinase 2 inhibits tumor growth and sensitizes cisplatin in patients with non-small cell lung cancer.

The present study investigated the role of microRNA-137-regulated AKT serine/threonine kinase 2 (AKT2) on tumor growth and cisplatin sensitivity in patients with non-small cell lung cancer (NSCLC). The results demonstrated that the expression of microRNA-137 in cisplatin-treated NSCLC patient tissue samples was markedly lower than that in healthy tissue samples. The disease-free survival and overall survival rates of patients with NSCLC exhibiting a high microRNA-137 expression were higher than the survival rates of patients with NSCLC exhibiting a low expression of microRNA-137.