The detection and utilization of volatile metabolomics in Klebsiella pneumoniae by gas chromatography-ion mobility spectrometry.

This research aimed to analyze the volatile compounds emitted during the proliferation of Klebsiella pneumoniae (K. pneumoniae) in the laboratory setting using gas chromatography-ion mobility spectrometry (GC-IMS) and to investigate the potential of volatile metabolomics for detecting carbapenemase-producing strains of K. pneumoniae.

Analysis and application of volatile metabolic profiles of : a preliminary GC-IMS-based study.

Nosocomial infections caused by () may pose serious risks to patients, and early identification of pathogenic bacteria and drug sensitivity results can improve patient prognosis. In this study, we clarified the composition and relative content of volatile organic compounds (VOCs) generated by in tryptic soy broth (TSB) using gas chromatography-ion mobility spectrometry (GC-IMS). We explored whether imipenem (IPM) could be utilized to differentiate between carbapenem-sensitive (CSEC) and carbapenem-resistant (CREC).

Gas Chromatography-Ion Mobility Spectrometry Reveals Acetoin as a Biomarker for Carbapenemase-Producing Klebsiella pneumoniae.

BACKGROUND This study aimed to detect the volatile organic compound (VOC), 3-hydroxy-2-butanone (acetoin) using gas chromatography-ion mobility spectrometry (GC-IMS) in antimicrobial-resistant Klebsiella pneumoniae (K. pneumoniae) carbapenemase (KPC)-producing bacteria. MATERIAL AND METHODS Using stromal fluid of blood culture bottles (BacT/ALERT® SA) as the medium, 3-hydroxy-2-butanone (acetoin) released by K.

Clinical Characteristics, Prognosis and Treatment of Bloodstream Infections with Complex in a Chinese Tertiary Hospital: A Retrospective Study.

Objective: This research aimed to analyze the clinical characteristics, prognosis, and antimicrobial treatment of bloodstream infections (BSI) caused by complex (ECC).

Methods: The clinical data of patients with bloodstream infections caused by complex from April 2017 to June 2023 were collected retrospectively. These data were then analyzed in subgroups based on the detection results of extended-spectrum β-lactamase (ESBL), 30-day mortality, and the type of antimicrobial agent used (β-lactam/β-lactamase inhibitor combinations (BLICs) or carbapenems).

Risk Factors for 30-Day Mortality in Patients with Bacteremic Pneumonia Caused by and : A Retrospective Study.

Objective: and are prevalent Gram-negative microorganisms responsible for pneumonia, as well as the primary pathogens causing bacteremic pneumonia. The objective of this research is to analyze the risk factors associated with bacteremic pneumonia caused by these pathogens and develop a predictive model.

Patients And Methods: This retrospective investigation encompassed a cohort of 252 patients diagnosed with or -induced bacteremic pneumonia between 2018 and 2022.

Judicious fabrication of bifunctionalized graphene oxide/MnFeO magnetic nanohybrids for enhanced removal of Pb(II) from water.

Novel ternary nanohybrids, bifunctionalized graphene oxide/MnFeO magnetic nanoparticles (PEHA-Phos-GO/MnFeO), were prepared by a facile method and applied for the removal of Pb(II) from aqueous solution. Attributing to the numerous amino and phosphate groups on the bifunctionalized GO nanosheets as well as the magnetic nanoparticles of MnFeO, PEHA-Phos-GO/MnFeO demonstrated high removal efficiency of Pb(II) and rapid magnetic separation. The 366.