Cytotoxic Polyhydroxy-Isoprenoids from .

Fungal-derived natural products continue to play a pivotal role in the discovery of drug agents for human, veterinary, and general agricultural use. The fungus presents a significant saprobic ascomycete whose metabolites remained hitherto unstudied. Herein we report the isolation of eight unprecedented secondary metabolites named neodidymelliosides A and B ( and ), neodidymelliol A (), and neodidymellioic acids A-E (-) produced by the submerged cultures of the fungus.

Lasiodipline G and other diketopiperazine metabolites produced by .

fungi are known to colonize plants as both pathogens and/or endophytes; hence, they can be exploited for their beneficial roles. Many compound classes from the genus have exhibited their potential biotechnological applications. Herein, we report two new metabolites 1 and 2 together with three known cyclo-(D-Ala-D-Trp) (3), indole-3-carboxylic acid (4) and a cyclic pentapeptide clavatustide B (5), isolated from the submerged cultures of a recently described species .

Antifungal properties of volatile organic compounds produced by MFLUCC 19-0493 isolated from leaves against and its post-harvest infections on strawberry fruits.

Fungal endophytes are microorganisms living symbiotically with a host plant. They can produce volatile organic compounds (VOCs) that have antimicrobial activity. This study aimed to isolate endophytic fungi from plants grown in Thailand and to investigate the antifungal properties of their VOCs against , a causal agent of anthracnose disease on post-harvest strawberry fruits.

In vitro and in vivo antifungal activity of Cuminum cyminum essential oil against Aspergillus aculeatus causing bunch rot of postharvest grapes.

Bunch rot in grapes is an aggressive disease and needs to be controlled during the postharvest period. We investigate the antifungal potential of Zanthoxylum bungeanum Maxim., Zanthoxylum rhetsa, Cuminum cyminum, Coriandrum sativum, and Zingiber montanum (J.

Characterisation of teaghrelin-like principles from Assam tea cultivated in Thailand.

Teaghrelins were identified as unique acylated flavonoid tetraglycosides and firstly reported in Chin-shin oolong tea. In the present study, two new teaghrelin-like compounds ( and ) were purified and characterised from Assam tea varieties collected in Thailand. Their chemical structures were constructed by the spectroscopic and spectrometric analysis.

Antifungal activity of 8-methoxynaphthalen-1-ol isolated from the endophytic fungus MFLUCC 17-0313 against the plant pathogenic fungus on tomatoes.

Thirty-four endophytic fungal isolates were obtained from the leaves of the medicinal plant , and their antagonistic activities against the growth of the common tomatoes plant pathogenic fungus were initially screened using a dual culture assay. The endophytic fungus MFLUCC 17-0313, which was later molecularly identified as , displayed the highest inhibition percentage (49.98%) in comparison to the others.

Essential Oil Compositions and Antibacterial and Antioxidant Activities of Five Lavandula stoechas Cultivars Grown in Thailand.

The essential oils of five Lavandula stoechas cultivars grown in Thailand were characterized for their volatile compounds using GC-FID and GC/MS methods as well as screened for antibacterial and antioxidant activities. Dried aerial parts, including flowers and stems from each cultivar, were subjected to hydrodistillation for 4 h. The essential oil yields were 0.

Production of eugenol from fungal endophytes sp. and sp. isolated from leaves.

Endophytic fungi, which colonize within a host plant without causing any apparent diseases, have been considered as an important source of bioactive secondary metabolites containing antimicrobial and antioxidant activities. The aim of this research was to isolate the endophytic fungi of and then to screen their antimicrobial and antioxidant activities. A total of 11 fungal endophytes were isolated from healthy leaves of belonging to six genera: , , , , , and .

Antibacterial potential of secondary metabolites produced by Aspergillus sp., an endophyte of Mitrephora wangii.

Mitrephora wangii, an ethnomedicinal plant, has been used as a natural antibiotic and immunity booster in Thailand. A total of 22 fungi were isolated from M. wangii flowers.

Antibacterial and Antioxidant Metabolites of Diaporthe spp. Isolated from Flowers of Melodorum fruticosum.

Fifty-two strains of endophytic fungi were isolated from flowers of the medicinal plant Melodorum fruticosum. Seven genera were identified including Alternaria, Aspergillus, Colletotrichum, Diaporthe, Fusarium, Greeneria and Nigrospora. All strains were cultured for 30 days and further macerated in ethyl acetate solvent for 3 days.