Background: Drug-induced liver injury (DILI) is one of the most common liver diseases. The crucial role of lipid droplets (LDs) and hydrogen peroxide (HO), two important biomarkers in the pathophysiology of DILI, has spurred considerable efforts to accurately visualize HO and LDs for elucidating their functions in the progression of DILI. However, construction of a single fluorescent probe that is able to simultaneously image HO and LDs dynamics remains to be a challenging task.
View Article and Find Full Text PDFChem Commun (Camb)
November 2024
Peroxynitrite (ONOO), as an important reactive nitrogen species, plays a pivotal role in the regulation of intracellular redox homeostasis, signal transduction, cell growth and metabolism, and other physiological processes. Organelles are important for regulating ONOO, and the dysregulation of ONOO in organelles is closely related to various diseases. Therefore, it is essential to monitor ONOO in cellular organelles, including mitochondria, lysosome, endoplasmic reticulum (ER), Golgi apparatus, and lipid droplets.
View Article and Find Full Text PDFExcitonic systems, facilitated by optical pumping, electrostatic gating or magnetic field, sustain composite particles with fascinating physics. Although various intriguing excitonic phases have been revealed via global measurements, the atomic-scale accessibility towards excitons has yet to be established. Here, we realize the ground-state interlayer exciton complexes through the intrinsic charge transfer in monolayer YbCl/graphite heterostructure.
View Article and Find Full Text PDFThe simple preparation of mesoporous NiS//MoS composite catalyst through a one-pot solvothermal method is presented. The improvement of the specific surface area (220 m/g) and the construction of the porous structure are realized by this method in the case of no support. The organics acts as a microscopic binder contribute to uniform stacking of MoS with NiS clusters.
View Article and Find Full Text PDFMechanoluminescence (ML) plays a vital role in various fields, and has gained increasing popularity over the past two decades. The widely studied materials that are capable of generating ML can be classified into two groups, self-powered and trap-controlled. Here, we demonstrate that both self-powered ML and trap-controlled ML can be achieved simultaneously in MgF:Tm.
View Article and Find Full Text PDFWell-dispersed PdIn bimetallic alloy nanoparticles (1-4 nm) were immobilized on mesostructured silica by an in situ capture-alloying strategy, and PdIn-InO interfaces were rationally constructed by changing the InO loading and reduction temperature. The catalytic performance for benzyl alcohol partial oxidation was evaluated, and a catalytic synergy was observed. The Pd-rich PdIn-InO interface is prone to be formed on the catalyst with a low InO loading after being reduced at 300 °C.
View Article and Find Full Text PDFSensors (Basel)
February 2023
Diffraction algorithms with adjustable magnification are dominant in holographic projection and imaging. However, the algorithms are limited by the Nyquist sampling conditions, and simulation results with inappropriate parameters sometimes appear with aliasing. At present, many diffraction algorithms have been proposed and improved, but there is a need for an overall analysis of their sampling conditions.
View Article and Find Full Text PDFLuminescence-based thermometry, especially the ratiometric temperature sensing technology, has attracted considerable attention recently due to its characteristics such as non-contact operating mode and strong capacity of resisting disturbance. Differing from the conventional strategy that usually needs continuous excitation, here an optical thermometry, which we have named the persistent luminescence intensity ratio (PLIR) thermometry, is proposed. The PLIR thermometry relies on the optical material SrF:Pr that could emit luminescence for several hours and even longer after being charged by X-ray.
View Article and Find Full Text PDFRev Sci Instrum
September 2022
An in-fiber Michelson interferometric sensor was presented by fabricating a concavity on the end face of a single mode fiber using a single CO laser pulse. Reflected beams from the bottom and air-cladding boundary of the concavity are coupled into the fiber core and superimpose to generate a two-beam in-fiber Michelson interferometer. Compared with other laser-machining methods where multiple scanning cycles with precise manipulation are needed, the proposed method is more straightforward because only a single laser pulse is used to construct the sensor.
View Article and Find Full Text PDFThe ultraviolet C (UVC) photon plays a key role in a broad spectrum of fields. With the implementation of the Minamata Convention, searching for a new way to achieve UVC light is highly desired. Here we develop a material of CaSiO:Pr that can emit UVC light upon excitation of a 450-nm laser or even a very cheap 450-nm LED, a fact confirmed by using a solar blind camera to capture UVC emission from CaSiO:Pr.
View Article and Find Full Text PDFα-RuCl, a promising material to accomplish the Kitaev honeycomb model, has attracted enormous interest recently. Mottness and p-d bonds play vital roles in generating Kitaev interactions and underpinning the potential exotic states of quantum magnets, and the van der Waals monolayer is considered to be a better platform to approach a two-dimensional Kitaev model than the bulk. Here, we worked out the growth art of an α-RuCl monolayer on a graphite substrate and studied its electronic structure, particularly the delicate orbital occupations, through scanning tunneling microscopy and spectroscopy.
View Article and Find Full Text PDFThe objective of the study was to elucidate the stearoyl-coenzyme A desaturase (SCD1)-dependent gene network of c9, t11-CLA biosynthesis in MAC-T cells from an energy metabolism perspective. The cells were divided into the CAY group (firstly incubated with CAY10566, a chemical inhibitor of SCD1, then incubated with trans-11-octadecenoic acid, (TVA)), the TVA group (only TVA), and the control group (without CAY, TVA). The c9, t11-CLA, and TVA contents were determined by gas chromatography.
View Article and Find Full Text PDFA novel, to the best of our knowledge, optical temperature measurement method is proposed, i.e., persistent luminescence intensity ratio (PLIR) thermometry.
View Article and Find Full Text PDFA balance between catalytic activity and product selectivity remains a dilemma for the partial oxidation processes because the products are prone to be overoxidized. In this work, we report on the partial oxidation of benzyl alcohol using a modified catalyst consisting of nanosized Au-Pd particles (NPs) with tin oxide (SnO) deposited on a mesoporous silica support. We found that the SnO promotes the autogenous reduction of PdO to active Pd species on the Au-Pd NP catalyst (SnO@AP-ox) before H reduction, which is due to the high oxophilicity of Sn.
View Article and Find Full Text PDFWe propose an agent-based model for predicting individual flight delays in an entire air traffic network. In contrast to previous work, more detailed parameter estimation methods were incorporated into the agent-based model, acting on the state transitions of agents. Specifically, a conditional probability model was proposed for modifying the expected departure time, which was used to indicate whether a flight had experienced the necessary waiting due to Ground Delay Programs (GDPs) or carrier-related reasons.
View Article and Find Full Text PDFWe report a green, template-free, and general one-pot method of endogenous growth of free-standing boehmite (AlOOH) nanosheets on a 3D-network 60 μm-Al-fiber felt through water-only hydrothermal oxidation reaction between Al metal and HO (2Al + 4HO → 2AlOOH + 3H). Content and morphology of AlOOH nanosheets can be finely tuned by adjusting the hydrothermal oxidation time length and temperature. Palladium is highly dispersed on such AlOOH endogenously formed on Al-fiber felt via incipient wetness impregnation method and as-obtained Pd/AlOOH/Al-fiber catalysts are checked in the CO coupling to dimethyl oxalate (DMO) reaction.
View Article and Find Full Text PDFA monolithic Ni-foam@PdNi(alloy) catalyst is tailored for coalbed methane deoxygenation via galvanically depositing Pd nanoparticles on a Ni-foam surface followed by in situ activation. Experimental and theoretical studies unanimously reveal that the in situ formed PdNi alloy contributes to high activity/selectivity, good stability and oscillation elimination.
View Article and Find Full Text PDFWe report a macroscopic stainless-steel-fiber@HZSM-5 core-shell catalyst by direct growth of 27 wt% HZSM-5 on a 3D microfibrous structure using 20 μm SS fibers, demonstrating dramatic selectivity and stability improvement in the MTP process. The unprecedented performance is due to the promotion of the olefin methylation/cracking cycle in methanol-to-hydrocarbon catalysis.
View Article and Find Full Text PDFMicrocrystalline cellulose (MCC)/nano-SiO2 composite fibers were processed from solutions in 1-allyl-3-methylimidazolium chloride (AMIMCl) by the method of dry-jet wet spinning. The oscillatory shear measurements demonstrated that the gel network formed above 10 wt% nano-SiO2 and the complex viscosity increased with increasing nano-SiO2. Remarkably, the shear viscosity of the nanofluids was even lower than solutions without nano-SiO2 under high shear rates.
View Article and Find Full Text PDFPolycrystalline BiFeO3 nanoparticles (size 30-50 nm) were prepared by a simple microwave synthesis technique. The nanoparticles were characterized by XRD, TEM and TG-DTA. The applied experiments show that they are very efficient for photo-catalytic decomposition of organic contaminants under irradiation ultraviolet frequency.
View Article and Find Full Text PDFRNA silencing is a conserved mechanism found ubiquitously in eukaryotic organisms. It has been used to regulate gene expression and development. In addition, RNA silencing serves as an important mechanism in plants' defense against invasive nucleic acids, such as viruses, transposons, and transgenes.
View Article and Find Full Text PDFRNA silencing is a potent antiviral response in plants. As a counterdefense, most plant and some animal viruses encode RNA silencing suppressors. In this study, we showed that Pns6, a putative movement protein of Rice ragged stunt virus (RRSV), exhibited silencing suppressor activity in coinfiltration assays with the reporter green fluorescent protein (GFP) in transgenic Nicotiana benthamiana line 16c.
View Article and Find Full Text PDFThe silent information regulator protein (Sir2) and its homologs are NAD(+)-dependent deacetylase enzymes that play important roles in a variety of physiological processes. However, the functions of the Sir2 family in plants are poorly understood. Here, we report that Arabidopsis AtSRT2, a homolog of yeast Sir2, negatively regulates plant basal defense against the pathogen Pseudomonas syringae pv.
View Article and Find Full Text PDFBranched-chain amino acid transaminases (BCATs) play a crucial role in the metabolic pathway of leucine, isoleucine and valine by catalyzing the last step of synthesis and/or the initial step of degradation of these amino acids. In this study, we characterized a new BCAT from Nicotiana benthamiana (NbBCAT, GeneBank accession No. EU194916), the deduced amino acid sequence of which exhibits a very high percentage of identity to the homologous enzymes from Solanum tuberosum (StBCAT-2, 91.
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