Publications by authors named "Chunxing Wu"

Purpose: The purpose of this study is to retrospectively analyze children treated conservatively in our hospital to explore the clinical characteristics of children with traumatic atlantoaxial joint infra-anterior dislocation complicating odontoid fracture and the therapeutic effects of treatment.

Methods: Patients with atlantoaxial joint infra-anterior dislocation complicating odontoid fracture received conservative treatment, which comprised three steps: cervical traction (2 weeks), plaster fixation (2 months), and brace fixation (3 months).

Results: We treated three patients (boy:girl = 0:3, mean age = 2.

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This study examined the effects of exogenous 2,4-epibrassinolide (EBR) on photosynthetic traits of 53 cowpea varieties under NaCl stress. The results of different analysis and correlation analysis showed that these 53 germplasm resources had rich genetic diversity, and significant correlations existed among various photosynthetic traits. Under NaCl stress, Pn was highly significantly positively correlated with Gs and Tr and extremely significantly negatively correlated with Ci.

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  • The study aimed to assess the effectiveness of Cross-Union surgery in treating tibial pseudarthrosis in children with neurofibromatosis type 1 (NF1).
  • Eight patients, aged between 1.8 and 13.3 years, had their clinical data analyzed for outcomes such as bone healing and any recurrence of fractures after surgery.
  • Results indicated an overall healing rate of 87.5% with no new fractures during follow-up, though some patients did experience minor leg length discrepancies and persistent ankle valgus.
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  • Osteofibrous dysplasia (OFD) commonly affects the tibia, leading to deformities and fractures; traditional surgical treatments pose risks and complications.* -
  • This study analyzed the outcomes of 4 children who underwent a new minimally invasive procedure combining tibial osteotomy with telescopic rod fixation to treat OFD-related tibial bowing.* -
  • Results showed no complications or deformity recurrence, with successful bone healing in an average of 3 months and significant improvements in function as measured by the MSTS score.*
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Developmental dysplasia of the hip (DDH) is a developmental disorder characterized by acetabular dysplasia leading to early osteoarthritis. This study examines the role of endoplasmic reticulum stress (ERS) in chondrocyte apoptosis and cartilage degeneration within a DDH model. In the rat model of DDH, created using a swaddling technique, significant deformities in the femoral head and acetabulum were observed, alongside an upregulation of matrix metalloproteinase-13 in acetabular cartilage.

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Background: In this study, the regularity of drug containing borneol proprietary Chinese medicine was mined, to provide reference for the clinical application and new drug research and development of borneol.

Methods: The database of proprietary Chinese medicines on Pharmaceutical Intelligence Network was searched for internal and external prescriptions that contained borneols and the diseases they treat. Microsoft Office Excel 2019 and SPSS Modeler 18.

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  • Ollier's disease in children leads to significant leg length discrepancies and deformities, which can be corrected through osteotomy and limb lengthening using external fixation.
  • The study compared two groups: nine patients with Ollier's disease undergoing 11 procedures and a control group of 28 patients with normal limb lengthening, assessing various metrics like correction angle and healing indexes.
  • Results showed that patients with Ollier's disease experienced faster healing and more effective deformity correction without a higher rate of complications compared to the control group.
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Objectives: Inappropriate treatment of Closed displaced phalangeal neck fractures (CDPNF) in children usually leads to poor outcomes.This study was to evaluate the clinical outcomes of closed/open reduction, age, and different types of fracture and Kirschner wire (K-wire) fixation in the treatment of CDPNF.

Materials And Methods: Participants: Sixty patients (male, 46 and female,14; right-handed, 35 and left-handed, 25; mean age, 7.

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Background: The metachronism of bilateral trigger thumb (TT) may lead to additional surgery under anesthesia. The aim of this study was to investigate the temporal development of bilateral TT, find risk factors for contralateral TT, and provide evidence for clinical practice.

Methods: A retrospective analysis was performed on children diagnosed with TT in our hospital from January 2016 to December 2019.

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Objectives: Congenital malformation, trauma, tumor, or metabolic disease can cause length deformity of the radius or ulna, affecting the appearance and function of the forearm. Osteotomy and lengthening with external fixation can obviously improve the length of the radius and ulna (LRU). However, the extent of lengthening required is still unclear.

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Background: The treatment of congenital pseudarthrosis of the tibia (CPT) remains a challenge because of the difficulties of achieving and maintaining bone union, as well as complications of joint deformity and limb-length discrepancy. The purpose of this study was to evaluate the efficacy of cross-union of the tibia and fibula in achieving union and preventing refracture for patients with refractory CPT as a complementary approach to improve upon conventional surgical treatments.

Methods: A retrospective study including patients with refractory CPT who attended our department between June 2014 and August 2020.

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Study Design: Retrospective case series.

Objectives: To evaluate the efficacy of growth-preserving posterior spinal column reconstruction surgery in children with collapsed vertebral eosinophilic granuloma (EG).

Methods: We retrospectively reviewed 15 confirmed cases of vertebral EG who met the inclusion and exclusion criteria from March 2015 to March 2018 in our hospital.

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Stem Leydig cells (SLCs) transplantation can restore testosterone production in rodent models and is thus a potential solution for treating testosterone deficiency (TD). However, it remains unknown whether these favorable effects will be reproduced in more clinically relevant large-animal models. Therefore, we assessed the feasibility, safety and efficacy of autologous SLCs transplantation in a testosterone-deficient non-human primate (NHP) model.

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The outbreak of Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged and spread rapidly throughout the world. As of February 29, 2020, 79 389 cases of COVID-19 have been reported, and the outbreak is linked to 2838 deaths. The population is generally susceptible to the disease, and differences in incubation periods after infection exist among individuals.

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In recent years, zwitterionic polymers have been frequently reported to modify various surfaces to enhance hydrophilicity, antifouling and antibacterial properties, which show significant potentials particularly in biological systems. This review focuses on the fabrication, properties and various applications of zwitterionic polymer grafted surfaces. The "graft-from" and "graft-to" strategies, surface grafting copolymerization and post zwitterionization methods were adopted to graft lots type of the zwitterionic polymers on different inorganic/organic surfaces.

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Objective: This study evaluated the efficacy of surgery for femoral neck fractures in children after a 24-h delay and the factors affecting the risk of complications.

Methods: The study included 16 children who underwent surgery after the first 24 h for femoral neck fractures. According to Delbet's classification, there were 2 type I, 11 type II, and 3 (four hips) type III cases.

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Brachydactyly includes shortening of digits due to abnormal development of phalanges, metacarpals, or both. It can occur either as an isolated malformation or with other anomalies as part of many congenital syndromes. It is included as one of the dysostosis groups affecting the limbs in the nosology and classification of genetic skeletal disorders.

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Purpose: The purpose of this study was to investigate whether the findings of Tc-99m pertechnetate salivary gland scintigraphy (SGS) can predict the outcome of sialoendoscopic intervention in patients with obstructive submaxillaritis.

Materials And Methods: Eleven patients with obstructive submaxillaritis were prospectively recruited. All patients underwent sialoendoscopy.

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