Publications by authors named "Chunxing Lu"
Article Synopsis
- The study aimed to investigate clinical features and gene mutations related to hereditary protein C deficiency in four families, focusing on their links to vascular thromboembolism.
- Four patients' clinical data were collected, along with venous blood samples for coagulation tests, followed by genetic analysis using PCR to identify mutations in the PROC gene.
- Results showed that all patients had impaired anticoagulation with specific mutations identified, including a newly reported one (c.1146_1146delT), which was classified as pathogenic and caused structural changes in the protein.
Myasthenia gravis (MG) is a common neuromuscular junction disorder and autoimmune disease mediated by several antibodies. Several studies have shown that genetic factors play an important role in MG pathogenesis. To gain insight into the epigenetic factors affecting MG, we report here genome-scale DNA methylation profiles of MG.
View Article and Find Full Text PDFDysplasminogenemia is a rare heritable disease caused by plasminogen (PLG) gene defects resulting in hypercoagulability. In this report we describe three notable cases of cerebral infarction (CI) complicated with dysplasminogenemia in young patients. Coagulation indices were examined on STAGO STA-R-MAX analyzer.
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