Auto-tuning of filtered proportional-integral-derivative controller for industrial processes under routine operating conditions.

In general, auto-tuning implementation of PID controllers relies on dual controllers, exciting/identification experiments or some prior knowledge on the process and hence the considerable cost on auto-tuning implementation occurs. To deal with such a problem, a new auto-tuning scheme of the FPID controller is developed for minimum variance tasks under routine operating conditions in which the closed-loop system is running without any external excitation other than natural disturbances. This paper reveals that the stochastic disturbance model can be uniquely determined from the first several terms of the impulse response coefficients of the closed-loop system when the precondition on the time delay and the order of the disturbance model is satisfied.

Anoectochilus roxburghii polysaccharide reduces D-GalN/LPS-induced acute liver injury by regulating the activation of multiple inflammasomes.

Background: Acute liver injury (ALI) is a serious syndrome with a high mortality rate due to viral infection, toxic exposure, and autoimmunity, and its severity can range from mildly elevated liver enzymes to severe liver failure. Activation of the nod-like receptor pyrin domain-containing 3 (NLRP3) inflammasome is closely associated with the development of ALI, and the search for an inhibitor targeting this pathway may be a novel therapeutic option. Anoectochilus roxburghii polysaccharide (ARP) is a biologically active ingredient extracted from Anoectochilus roxburghii with immunomodulatory, antioxidant, and anti-inflammatory bioactivities and pharmacological effects.

Data-driven approach for time-delay estimation of industrial processes.

An accurate estimate of time delay is of crucial importance for control tasks such as performance assessment and controller design. In this paper, a novel data-driven approach to time-delay estimation is developed for a process subject to industrial background disturbances, in which the closed-loop output data under the routine operating conditions is only required. The practical solutions are proposed to estimate the time delay based on the estimated impulse response of the closed loop that is estimated online by utilizing the output data.

A data-driven approach for on-line auto-tuning of minimum variance PID controller.

A data-driven approach for on-line tuning of minimum variance (MV) PID controller is proposed in this paper for a linear system subject to stochastic disturbances, in which none of a prior knowledge or/and external excitation signals is required. The main procedure is that two different rough tuning controllers are employed and switched from one to another such that two sets of output data are collected under routine operating conditions. Subsequently, based on FCOR (Filtering and CORrelation analysis) algorithm, the corresponding linear MV controller is estimated on-line for the linear system.

Semidiscrete Quantum Droplets and Vortices.

We consider a binary bosonic condensate with weak mean-field (MF) residual repulsion, loaded in an array of nearly one-dimensional traps coupled by transverse hopping. With the MF force balanced by the effectively one-dimensional attraction, induced in each trap by the Lee-Hung-Yang correction (produced by quantum fluctuations around the MF state), stable on-site- and intersite-centered semidiscrete quantum droplets (QDs) emerge in the array, as fundamental ones and self-trapped vortices, with winding numbers, at least, up to five, in both tightly bound and quasicontinuum forms. The application of a relatively strong trapping potential leads to squeezing transitions, which increase the number of sites in fundamental QDs and eventually replace vortex modes by fundamental or dipole ones.

Bioaugmentation of Exogenous Strain Rhodococcus sp. 2G Can Efficiently Mitigate Di(2-ethylhexyl) Phthalate Contamination to Vegetable Cultivation.

This work developed a bioaugmentation strategy that simultaneously reduced soil di(2-ethylhexyl) phthalate (DEHP) pollution and its bioaccumulation in Brassica parachinensis by inoculating the isolated strain Rhodococcus sp. 2G. This strain could efficiently degrade DEHP at a wide concentration range from 50 to 1600 mg/L and transformed DEHP through a unique biochemical degradation pathway that distinguished it from other Rhodococcus species.

Differences in Root Physiological and Proteomic Responses to Dibutyl Phthalate Exposure between Low- and High-DBP-Accumulation Cultivars of Brassica parachinensis.

Di- n-butyl phthalate (DBP), as an endocrine-disrupting chemical that tends to be accumulated in crops, poses great risks to human health through the food chain. To identify the molecular mechanism underlying differences in their DBP accumulation, the root physiological and proteomic responses to DBP stress of two Brassica parachinensis cultivars, a high-DBP accumulator (Huaguan) and a low-DBP accumulator (Lvbao), were investigated. Root damage of greater severity and significantly greater ( p < 0.

[Optimization of extraction procedure of psammosilene tunicoides by uniform design with pharmacodynamic index].

Objective: For anti-inflammation, relieving pain and decreasing acute toxicity, the best condition for extracting procedure of Psammosilene tunicoides was chosen. And the relationships between several solvent extracts and pharmacodynamic index were studied.

Method: Uniform design with multi-targets was used in the optimization process, and the evaluate index were the results of anti-inflammation, relieving pain and LD50 were employed as the evaluating indexes.

[Selection of the receptor fluid based on main drug' s dissolvability in the in-vitro skin permeation study].

Objective: To select the receptor fluid used in the in-vitro skin permeation study of CVD from Shuxin transdermal patch.

Methods: The saturated concentration of CVD in different receptor fluid was determined by RP-HPLC with precolumn ultraviolet derivatization. And the selection of receptor fluid was based on main drug's dissolvability.