Publications by authors named "Chunnan Wu"

In acute intestinal ischemia, the progression of ischemia varies across different layers of intestinal tissue. We established a mouse model and used swept-source optical coherence tomography (OCT) to observe the intestinal ischemic process longitudinally in different tissue layers. Employing a method that combines asymmetric gradient filtering with adaptive weighting, we eliminated the vessel trailing phenomenon in OCT angiograms, reducing the confounding effects of superficial vessels on the imaging of deeper vasculature.

View Article and Find Full Text PDF

Developing biocompatible and antibacterial materials with biodegradable polymers is an ideal strategy to improve public health problems and plastic pollution simultaneously. In the present study, novel biocompatible and antibacterial poly (-lactic acid) (PLLA, coded as P)/TEMPO-oxidized cellulose nanofiber (TOCNF, coded as T)‑silver nanoparticle (AgNP, coded as A) films were first developed. The core/shell PT Pickering emulsion was prepared by sonication treatment.

View Article and Find Full Text PDF

Fucoxanthin is a natural pigment widely distributed in macroalgae and microalgae. An orange-colored xanthophyll, it has several bioactive effects, including anticancer, anti-obesity, oxidative stress reduction, and anti-inflammation. Acute lung injury (ALI) caused by acute infections or injurious stimuli to the lung tissues is a severe pulmonary inflammatory disease.

View Article and Find Full Text PDF

Development of intact oxidized starch granules by regioselective oxidation technology is of interest and provides a new research direction for oxidized starch. In this study, new sodium tetrahydridoborate (NaBH)-treated oxidized starch (OS-BH) granules were prepared by a one-pot method, where native corn starch (NS) granules were oxidized by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)/sodium hypochlorite (NaClO) system followed by reduction with NaBH. Oxidized starch (OS) granules without NaBH reduction were also prepared to investigate the effect of C6 aldehyde groups remained after TEMPO-mediated oxidation on properties of the granules.

View Article and Find Full Text PDF

Despite minoxidil and finasteride already being approved by the Food and Drug Administration (FDA) for the treatment of hair loss, it is important to identify new and innovative treatments for hair loss, such as looking for a solution in Chinese herbal medicine. One such treatment to consider is BeauTop (BT), whose primary ingredients include (T.Nees), C.

View Article and Find Full Text PDF

Enzyme immobilization can increase enzyme reusability to reduce cost of industrial production. Ginkgo biloba leaf extract is commonly used for medical purposes, but it contains ginkgolic acid, which has negative effects on human health. Here, we report a novel approach to solve the problem by degrading the ginkgolic acid with immobilized-laccase, where core/shell composite nanoparticles prepared by coaxial electrospraying might be first applied to enzyme immobilization.

View Article and Find Full Text PDF

The aim of this study is to simultaneously evaluate anti-oxidative and anti-inflammatory activities of the hop extracts by different solvents. Hop water extract (HWE) and hop ethanol extracts (HEEs) were prepared by extracting hop pellets with hot water at 90 °C and ethanol solutions (55%, 75%, and 95%), respectively. Bioactive compound such as α-acid, β-acid, total phenolic, and total flavonoid contents were determined.

View Article and Find Full Text PDF

Background: To investigate the magnetic resonance imaging (MRI) features of orbital Langerhans cell histiocytosis (LCH) to improve diagnostic accuracy.

Methods: We retrospectively reviewed clinical manifestations and MRI findings of 23 patients with histopathology-confirmed LCH of the orbit. The findings were evaluated for the following: (a) symptoms, (b) disease duration, (c) location, (d) configuration, (e) margin, (f) MR imaging signal intensity and enhanced performance.

View Article and Find Full Text PDF

Aim: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography (PDT).

Methods: Twenty patients with orbital space-occupying lesions and 25 age- and gender-matched healthy persons were included. All patients and controls underwent routine orbital magnetic resonance imaging and diffusion tensor imaging (DTI), using a 3.

View Article and Find Full Text PDF

Novel pH-responsive granules with tunable volume from oxidized starch granules were prepared from waxy and normal corn starches using 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation and pregelatinization. Conditions of both oxidation and pregelatinization were designed on the basis of maintaining intact granules' morphology. Carboxylate groups at C6 in anhydroglucose of the oxidized starch acting as pH-responsivity controllers were introduced to by TEMPO/NaClO/NaClO system at pH 6.

View Article and Find Full Text PDF

Biocompatible bacterial cellulose pellicle (BCP) is a candidate for biomedical material such as wound dressing. However, due to lack of antibacterial activity, to grant BCP with the property is crucial for its biomedical application. In the present study, BCP was modified by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation using TEMPO/NaClO/NaBr system at pH 10 to form TEMPO-oxidized BCP (TOBCP) with anionic C6 carboxylate groups.

View Article and Find Full Text PDF

Background: Very few studies have been made to investigate functional activity changes in occult spastic diplegic cerebral palsy (SDCP). The purpose of this study was to analyze whole-brain resting state regional brain activity and functional connectivity (FC) changes in patients with SDCP.

Methods: We examined 12 occult SDCP and 14 healthy control subjects using resting-state functional magnetic resonance imaging.

View Article and Find Full Text PDF

Controlling the assembly modes of different crystalline nanoparticles in composites is important for the expression of specific characteristics of the assembled structures. We report a unique procedure for increasing water contact angles (CAs) of composite film surfaces via the assembly of two different hydrophilic components, nanocellulose fibrils and nanoclay platelets. The nanocellulose fibrils and nanoclay platelets used have ionic groups on their surfaces in high densities (∼1 mmol g(-1)) and have no hydrophobic surface.

View Article and Find Full Text PDF

Rationale And Objectives: The objective of this study was to determine the diagnostic accuracy of contrast-enhanced magnetic resonance angiography (MRA) when used in the preoperative evaluation of hepatic vascular anatomy in living liver donors.

Materials And Methods: A computer-assisted literature searching of EMBASE, PubMed (MEDLINE), and the Cochrane library databases was conducted to identify potentially relevant articles which primarily examined the utility of contrast-enhanced MRA in the preoperative evaluation of hepatic vascular anatomy in living liver donors. We used the Q statistic of chi-squared value test and inconsistency index (I-squared, I(2)) to estimate the heterogeneity of the data extracted from all selected studies.

View Article and Find Full Text PDF

Purpose: To describe the magnetic resonance imaging (MRI) features of orbital rhabdomyosarcoma (RMS).

Methods: Thirty-nine patients with histopathologically confirmed orbital RMS were retrospectively reviewed. All patients underwent orbital conventional MRI, including axial, sagittal, and coronal T1-weighted, T2-weighted, and postcontrast T1-weighted sequences.

View Article and Find Full Text PDF

A highly tough and transparent film material was prepared from synthetic saponite (SPN) nanoplatelets of low aspect ratios and nanofibrillar cellulose. The nanofibrillar cellulose was chemically modified by topological surface oxidation using 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) as a catalyst. Both synthetic SPN nanoplatelets and TEMPO-oxidized cellulose nanofibrils (TOCNs) have abundant negative charges in high densities on their surfaces and are dispersed in water at the individual nanoelement level.

View Article and Find Full Text PDF

Transparent and flexible cellulose-clay (montmorillonite, MTM) nanocomposite films are prepared from cellulose/LiOH/urea solutions. The results show that the composites possess intercalated nanolayered structures. Almost no Na ions are present in MTM, probably because they are substituted by Li ions.

View Article and Find Full Text PDF

Nanocellulose/montmorillonite (MTM) composite films were prepared from 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-oxidized cellulose nanofibrils (TOCNs) with an aspect ratio of >200 dispersed in water with MTM nanoplatelets. The composite films were transparent and flexible and showed ultrahigh mechanical and oxygen barrier properties through the nanolayered structures, which were formed by compositing the anionic MTM nanoplatelet filler in anionic and highly crystalline TOCN matrix. A composite film with 5% MTM content had Young's modulus 18 GPa, tensile strength 509 MPa, work of fracture of 25.

View Article and Find Full Text PDF