Publications by authors named "Chunmei Yun"

Ethnopharmacological Relevance: Traditional Chinese medicine (TCM) is considered a valuable asset in China's medical tradition. YPF is a classic prescription that has been derived from the "Jiu Yuan Fang" formula and consists of three herbs: Huangqi (Astragalus membranaceus Bunge), Baizhu (Atractylodes rubra Dekker), and Fangfeng (Saposhnikovia divaricata (Turcz.) Schischk).

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Objectives: The SABINA CHINA study aimed to determine prescription data for asthma medication with a focus on SABA and ICS in a representative population of patients with asthma in China.

Methods: SABINA China was a multicentre, observational, cross-sectional study with data collected retrospectively from a convenience sample of 25 tertiary centres across China. Patients (age ⩾ 12 years) with ⩾3 consultations/year were enrolled.

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COVID-19 is spreading widely, and the pandemic is seriously threatening public health throughout the world. A comprehensive study on the optimal sampling types and timing for an efficient SARS-CoV-2 test has not been reported. We collected clinical information and the values of 55 biochemical indices for 237 COVID-19 patients, with 37 matched non-COVID-19 pneumonia patients and 131 healthy people in Inner Mongolia as control.

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Background: High-flow nasal cannula (HFNC) can improve ventilatory function in patients with acute COPD exacerbation. However, its effect on clinical outcomes remains uncertain.

Methods: This randomized controlled trial was conducted from July 2017 to December 2020 in 16 tertiary hospitals in China.

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Background: In 2017, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) removed spirometry as a criterion for classifying GOLD risk groups (A-D, low-high risk).

Methods: In this cross-sectional observational study in China, we used the GOLD 2016 (spirometry included) and 2018 (spirometry eliminated) criteria for classifying GOLD risk groups to describe: the proportion of patients with chronic obstructive pulmonary disease (COPD) in each GOLD risk group; disease severity; demographics and comorbidities. Patients aged ≥40 years with a clinical COPD diagnosis for ≥1 year were included.

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Article Synopsis
  • Lung nodules present diagnostic challenges, leading to misclassification and increased healthcare costs. A protocol aims to assess a liquid biopsy classifier's effectiveness compared to physician estimates for diagnosing nodules and reducing unnecessary biopsies.
  • A study will involve 10,560 patients with non-calcified pulmonary nodules monitored for 2 to 3 years, evaluating diagnostic accuracy through various methods, including a ctDNA methylation classifier.
  • The goal is to determine the classifier's precision in distinguishing between benign and malignant nodules, potentially improving patient outcomes and reducing healthcare burdens.
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Background: The difference in expression of sputum cells types between the two main types of chronic obstructive pulmonary disease (COPD) is largely unknown. This study aims to investigate the difference and then wants to depend on sputum cells sorting to direct the treatment of COPD.

Methods: A total of 218 patients with stable COPD (FEV1 < 80%) were selected.

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