Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.

Ovarian cancer (OC) is a common gynecological malignant tumor with poor prognosis. One form of controlled cell death that requires iron is ferroptosis. This study utilized TCGA data analysis to identify differentially expressed genes (DEGs) related to ferroptosis in OC, revealing 2,333 up-regulated and 4,073 down-regulated genes.

Identification and functional characterization of ABC transporters for selenium accumulation and tolerance in soybean.

ATP-binding cassette (ABC) transporters were crucial for various physiological processes like nutrition, development, and environmental interactions. Selenium (Se) is an essential micronutrient for humans, and its role in plants depends on applied dosage. ABC transporters are considered to participate in Se translocation in plants, but detailed studies in soybean are still lacking.

Illumina RNA and SMRT Sequencing Reveals the Mechanism of Uptake and Transformation of Selenium Nanoparticles in Soybean Seedlings.

Selenium (Se) is an essential element for mammals, and its deficiency in the diet is a global problem. Agronomic biofortification through exogenous Se provides a valuable strategy to enhance human Se intake. Selenium nanoparticles (SeNPs) have been regarded to be higher bioavailability and less toxicity in comparison with selenite and selenate.

Effect of Nano-Selenium on Nutritional Quality of Cowpea and Response of ABCC Transporter Family.

It is an important way for healthy Selenium (Se) supplement to transform exogenous Se into organic Se through crops. In the present study, was selected as a test material and sprayed with biological nano selenium (SeNPs) and NaSeO, and its nutrient composition, antioxidant capacity, total Se and organic Se content were determined, respectively. Further, the response of ABC transporter family members in cowpea to different exogenous Se treatments was analyzed by transcriptome sequencing combined with different Se forms.

Selenium Regulates Antioxidant, Photosynthesis, and Cell Permeability in Plants under Various Abiotic Stresses: A Review.

Plant growth is affected by various abiotic stresses, including water, temperature, light, salt, and heavy metals. Selenium (Se) is not an essential nutrient for plants but plays important roles in alleviating the abiotic stresses suffered by plants. This article summarizes the Se uptake and metabolic processes in plants and the functions of Se in response to water, temperature, light, salt, and heavy metal stresses in plants.

A lung adenocarcinoma patient with fusion and germline mutation achieves long progression-free survival from sintilimab combined with niraparib after failure of inhibitors: a case report.

Background: Lung cancer is a malignant tumor with high morbidity and mortality worldwide. At present, the main treatment methods for patients with advanced non-small cell lung cancer (NSCLC) include molecular targeted therapy and immunotherapy. The efficacy rate of immune checkpoint inhibitor (ICI) monotherapy is relatively low.

Endostar Plus Apatinib Successfully Achieved Long Term Progression-Free Survival in Refractory Ovarian Cancer: A Case Report and Literature Review.

Background: Ovarian cancer (OC) is a common malignancy in the gynecological tumor. Standard treatment for ovarian cancer is surgery and chemotherapy based on paclitaxel and platinum. However, traditional chemotherapy for ovarian cancer is limited by drug resistance and systemic side effects.

Association Between Urinary Stress Incontinence and Levator Avulsion Detected by 3D Transperineal Ultrasound.

Purpose:  To determine the association between levator avulsion and urinary stress incontinence (USI) by 3/4D transperineal ultrasound.

Materials And Methods:  842 patients who were admitted to our hospital from 2016 to 2019 were recruited for our study. 3D/4D transperineal ultrasound was performed.

Efficient Removal of Cr(VI) Ions by a Novel Magnetic 4-Vinyl Pyridine Grafted NiSiO(OH) Multiwalled Nanotube.

The contamination of water systems by heavy metals greatly threatens human health and ecological safety. An efficient adsorbent is critical for the removal of these contaminants. In this work, magnetic NiSiO(OH) nanotubes (NTs) have been synthesized via in situ hydrothermal reduction and further functionalized by grafting poly(4-vinyl pyridine) (P4VP) brushes on its surface via atom transfer radical polymerization.

Effects of Wu Qin xi Qigong exercise on physical functioning in elderly people with knee osteoarthritis: A randomized controlled trial.

Aim: Exercise therapy is a key intervention in the management of knee osteoarthritis (OA). This study aimed to test the 6-month effectiveness of Wu Qin Xi Qigong (WQXQ) exercise versus a conventional physical therapy (control group [CG]) on physical functioning in patients with early knee OA.

Methods: This study was a 6-month follow-up from a randomized controlled trial.

Chemical Cues Induced from Fly-Oviposition Mediate the Host-Seeking Behaviour of (Hymenoptera: Braconidae), an Effective Egg Parasitoid of (Diptera: Tephritidae), within a Tritrophic Context.

is a solitary endoparasitoid that parasitizes a variety of tephritid species. Native to the Indo-Australian region, it is currently exploited worldwide as a biological control agent due to its exceptional efficiency in reducing pest populations. The efficiency of any biological control program is affected by the host location ability of the parasitoids.

PAMPS--NiSiO(OH) multiwalled nanotubes as a novel nano-sorbent for the effective removal of Pb(ii) ions.

The existence of Pb(ii) ions in water systems poses significant potential hazards to public health and the environment. In the present study, poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS) brush-modified NiSiO(OH) nanotubes were prepared, and their adsorption efficiency against the Pb(ii) ions was investigated. The characterization results of FTIR spectroscopy, TGA, TEM, and XPS indicated the successful grafting of PAMPS on the surface of free NiSiO(OH) NTs, and the prepared PAMPS--NiSiO(OH) NTs exhibited a 6-8 nm grafting layer, which could provide abundant binding sites for metal adsorption.

Red cell distribution width in coronary heart disease: prediction of restenosis and its relationship with inflammatory markers and lipids.

Background: Red cell distribution width (RDW) is associated with a poor prognosis and adverse events in cardiovascular diseases. The aims of this study were to investigate the relationship between serum RDW levels and outcomes after percutaneous coronary intervention and to identify potential novel laboratory markers for evaluating the risk of in-stent restenosis (ISR) with stable angina pectoris.

Methods: A total of 261 patients with coronary heart disease from Dongfeng General Hospital implanted with a coronary drug-eluting stent (DES) were enrolled in the study.

Effect of health Baduanjin Qigong for mild to moderate Parkinson's disease.

Aim: The present study investigated the effectiveness of Baduanjin Qigong on symptoms related to gait, functional mobility and sleep in Parkinson disease (PD) patients.

Methods: A total of 100 patients (age 67.53 ± 8.

Efficacy of Liuzijue Qigong in Individuals with Chronic Obstructive Pulmonary Disease in Remission.

Objectives: To investigate the effectiveness of a 6-month Liuzijue qigong (LQG) program in promoting physical and psychosocial function in individuals with chronic obstructive pulmonary disease (COPD).

Design: Single-blind, randomized controlled trial.

Setting: Seven hospital respiratory care centers in Beijing.