Synopsis of recent research by authors named "Chunling Zeng"
- Chunling Zeng's recent research focuses on both cancer biology and organic chemistry, particularly exploring the genomic and transcriptomic characteristics of gastrointestinal stromal tumors (GISTs) and the catalytic processes in steroid hydrogenation.
- In the study of GISTs, Zeng identified a notable genomic landscape with low mutation burden but significant copy number variations, and elucidated the mechanism by which SETD2 inactivation can sensitize cancer cells to immune checkpoint inhibitors.
- Zeng's work in organic chemistry includes innovations in synthesizing 3-hydroxyl steroids and optimizing the production of lithocholic acid, highlighting the importance of regio- and chemoselectivity in catalytic reactions, while also investigating environmental factors affecting ozone formation sensitivity using satellite data.
