Background: Approximately 1-2% of non-small cell lung cancer (NSCLC) patients harbor RET (rearranged during transfection) fusions. The oncogenic RET fusions could lead to constitutive kinase activation and oncogenesis.
Methods: 1746 Chinese NSCLC patients were analyzed in this study.
Background: The prevalence of patients newly diagnosed with early-stage lung adenocarcinoma (LUAD) is growing alongside significant advances in screening approaches. This study aimed to construct ferroptosis-related gene score (FRGscore) for predicting recurrence, explore immune-molecular characteristics, and determine the benefit of immunotherapy in distinct ferroptosis-based patterns and FRGscore-defined subgroups.
Methods: A total of 1,085 early-stage LUAD patients from four independent cohorts were included.
Background: Cancer stem cells (CSCs) induces tumor metastasis and recurrence. However, the role of CSCs in molding the tumor immune microenvironment (TIME) is largely inexplicit. This study aimed to comprehensively characterize the stemness of esophageal cancer (EC) and correlate the stemness patterns with TIME.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
August 2013
Objective: To investigate early serum lipid profiles in preterm infants and their relationship with neonatal respiratory distress syndrome (RDS).
Methods: Appropriate-for-gestational-age (AGA) preterm infants were grouped according to gestational age (GA) or birth weight (BW). AGA full-term infants were randomly selected as the control group.
Background: Listeria monocytogenes infection is not commonly reported in China. Increasing the awareness of neonatal listeriosis is necessary.
Methods: Six cases of neonatal listeriosis were diagnosed in the neonatal intensive care unit at Beijing Obstetrics & Gynecology Hospital in 2008.