Development of a HPLC Method for the Quantitative Determination of Capsaicin in Collagen Sponge.

Controlling the concentration of drugs in pharmaceutical products is essential to patient's safety. In this study, a simple and sensitive HPLC method is developed to quantitatively analyze capsaicin in collagen sponge. The capsaicin from sponge was extracted for 30 min with ultrasonic wave extraction technique and methanol was used as solvent.

Determination of sinomenine in cubosome nanoparticles by HPLC technique.

We applied HPLC technique to quantitatively analyze sinomenine in cubosome nanoparticles. The chromatographic method was performed by using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.

An association study between polymorphisms of the fractalkine receptor gene, CX3CR1, and cerebral infarction in the Han Chinese population.

Objective: The aim of this study was to investigate the association between polymorphisms of CX3CR1 and the occurrence, neurological rehabilitation and 3-month outcome of cerebral infarction in the Han Chinese population.

Methods: We investigated the V249I and T280M mutations of CX3CR1 in 308 consecutive Han Chinese patients that were diagnosed with cerebral infarction and 294 age- and gender-matched healthy control subjects. The patients were classified with Oxfordshire Community Stroke Project (OCSP) classification, evaluated with a National Institute of Health Stroke Scale (NIHSS) score for an acute stage of stroke and assessed with a Barthel Index (BI) score 3months after stroke.