Purpose: This study aimed to clarify the formation and fixation of the annulus of Zinn (AZ) and its relationship with the extraocular muscles by using ultrathin plastination and three-dimensional models.
Methods: Eighteen cadaveric heads (36 sides of the orbital apex) were plastinated to coronal (16 sides), sagittal (13 sides), and horizontal (5 sides) ultrathin plastination sections to be investigated at both macroscopic and microscopic levels. One cadaveric head was used for endoscopic dissection to identify anatomic landmarks.
The medial wall of the cavernous sinus (CS) has a significant role in evaluation and treatment of pituitary adenomas. This study was conducted to clarify the fine architecture of the medial wall and medial compartment of the CS at both macro- and micro-levels in twenty-one human cadaveric heads by using the epoxy sheet plastination technique. The sellar part medial wall is an intact dural layer that separates the CS from the pituitary gland.
View Article and Find Full Text PDFHigh-mobility group box protein 1 (HMGB1), a nuclear protein that plays a significant role in DNA architecture and transcription, was correlated with the progression of some types of cancer. However, the role of HMGB1 in endometrial cancer cell invasion and metastasis remains unexplored. HMGB1 expression was initially assessed by immunohistochemistry and reverse transcription-quantitative polymerase chain reaction (RT-qPCR) in normal endometrial tissue and endometrial carcinoma tissue.
View Article and Find Full Text PDFObjective: To develop a LC-MS method for the determination of senkyunolide I (SI) in rat plasma, in order to observe whether there is significant change in the pharmacokinetics parameters of complex prescriptions of Huoluoxiaolingdan (HLXL) and single herbal extracts from Ligusticum chuanxiong Hort. in rats, and assess the effect of other components in HLXL on the pharmacokinetics of SI.
Method: Twelve male Sprague-Dawley (SD) rats were randomly divided into two groups, and orally administered with extract from HLXL and L.