Identification of proteins interacting with NOD2 and their role in macrophage inflammatory response.

(, Mp) is a cell wall-deficient microorganism known to cause chronic respiratory infections in both children and adults. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is an intracellular pattern recognition receptor primarily responsible for identifying muramyl dipeptide (MDP) found in bacterial cell walls. Previous experiments have demonstrated that induces macrophage autophagy through NOD2.

Extracellular Vesicles Released from Macrophages Infected with Stimulate Proinflammatory Response via the TLR2-NF-κB/JNK Signaling Pathway.

(, Mp) is an intracellular pathogen that causes pneumonia, tracheobronchitis, pharyngitis, and asthma in humans and can infect and survive in the host cells leading to excessive immune responses. Extracellular vesicles (EVs) from host cells carry components of pathogens to recipient cells and play a role in intercellular communication during infection. However, there is limited knowledge on whether EVs derived from -infected macrophages play as intercellular messengers and functional mechanisms.

[Dickkopf-1 inhibits the secretion of MUC5AC induced by P1-C in mouse lung epithelial cells].

is the most common pathogen of respiratory tract infection in children and adults. Clinical observation shows that . infection can cause massive mucus secretion in the respiratory tract, which makes the breathing of patients difficult.

Reserve of Wnt/β-catenin Signaling Alleviates Mycoplasma pneumoniae P1-C-induced Inflammation in airway epithelial cells and lungs of mice.

Mycoplasma pneumoniae (M. pneumoniae) is the most common pathogen of respiratory tract infections in both children and adults. M.