Publications by authors named "Chunhui Qin"
Background: Performing spinal anesthesia in elderly patients with spine degeneration is challenging for novice practitioners. This stratified randomized controlled trial aims to compare the effectiveness of mixed reality-assisted spinal puncture (MRasp) with that of landmark-guided spinal puncture (LGsp) performed by novice practitioners in elderly patients.
Methods: This prospective, single-center, stratified, blocked, parallel randomized controlled trial will include 168 patients (aged ≥ 65 years) scheduled for elective surgery involving spinal anesthesia.
Article Synopsis
- A pilot study compared mixed reality-assisted spinal puncture (MRasp) to landmark-guided spinal puncture (LGsp) among novice practitioners performing spinal anaesthesia on elderly patients (age ≥65).
- Results showed that the MRasp group had significantly fewer needle insertion attempts (1.0 vs 2.0) and a higher rate of successful first-attempt needle insertion (72.2% vs 44.4%).
- Although MRasp improved efficiency, the overall incidence of perioperative complications was similar in both groups, indicating the need for further randomized controlled trials to confirm these findings.
Rationale And Objectives: Extraction of intratumoral and peritumoral radiomics features combined with clinical factors to establish nomograms to predict high-grade patterns (micropapillary and solid) of invasive adenocarcinoma of the lung (IAC).
Materials And Methods: A retrospective study was conducted on 463 patients with pathologically confirmed IAC. Patients were randomized in a 7:3 ratio into a training cohort (n = 324) and a testing cohort (n = 139).
Article Synopsis
- FAM3 family genes are significant in the development of various cancers, influencing factors like prognosis, immune response, and drug sensitivity, though their exact role in pan-cancer remains unclear.
- This study analyzed data from multiple databases and conducted experiments, specifically focusing on the effects of FAM3C in pancreatic cancer, revealing that its expression significantly affects tumor characteristics and patient outcomes.
- Results showed that FAM3 family genes are differentially expressed in several cancers, correlate with immune subtypes, and that FAM3C expression increases tumor cell proliferation and invasion while decreasing apoptosis.
Accuracy Evaluation Trial of Mixed Reality-Guided Spinal Puncture Technology.
Ther Clin Risk Manag
July 2023
Purpose: To evaluate the accuracy of mixed reality (MR)-guided visualization technology for spinal puncture (MRsp).
Methods: MRsp involved the following three steps: 1. Lumbar spine computed tomography (CT) data were obtained to reconstruct virtual 3D images, which were imported into a HoloLens (2nd gen).
Background: The simulation is one of the basic methods of medical education, which is often used for procedural skills training. However, the existing simulator lacks internal anatomical landmarks. The study developed a mixed-reality stimulator and evaluated its usability and feasibility in lumbar puncture training.
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