TEFM facilitates uterine corpus endometrial carcinoma progression by activating ROS-NFκB pathway.

Background: Mitochondrial transcription elongation factor (TEFM) is a recently discovered factor involved in mitochondrial DNA replication and transcription. Previous studies have reported that abnormal TEFM expression can disrupt the assembly of mitochondrial respiratory chain and thus mitochondrial function. However, the role of TEFM on Uterine corpus endometrial carcinoma (UCEC) progression remains unclear.

Development and validation of a clinical prediction model for blastocyst formation during IVF/ICSI-ET.

Purpose: This study aims to create and validate a clinical model that predict the probability of blastocyst formation in IVF/ICSI-ET cycles.

Methods: This study employed a retrospective methodology, gathering data from 4961 cleavage-stage embryos that cultured in the reproductive center's of the Fourth Hospital of Hebei Medical University between June 2020 and March 2024. 3472 were in the training set and 1489 were in the validation set when it was randomly split into the training set and validation set in a 7:3 ratio.

Differential distribution of fibrovascular proliferative membranes in 25-gauge vitrectomy for proliferative diabetic retinopathy.

Aim: To analyze the distribution of fibrovascular proliferative membranes (FVPMs) in proliferative diabetic retinopathy (PDR) patients that treated with pars plana vitrectomy (PPV), and to evaluate the outcomes separately.

Methods: This was a retrospective and cross-sectional study. Consecutive 25-gauge (25-G) PPV cases operated for PDR from May 2018 to April 2020.

Study on segmentation of blasting fragment images from open-pit mine based on U-CARFnet.

Bench blasting is the primary means of production in open-pit metal mines. The size of the resulting rock mass after blasting has a significant impact on production cost. Currently, the ore fragment size is obtained mainly through manual measurement or estimation with the naked eye, which is inefficient and inaccurate.

Tenofovir disoproxil fumarate mediates neuronal injury by inducing neurotoxicity.

Purpose: Highly active antiretroviral therapy (HAART) is an accepted treatment option for patients with virus infection. Mounting evidence indicated that persistent HAART treatment is implicated with increased morbidity of HIV-associated neurocognitive disorders (HAND) in patients. Tenofovir disoproxil fumarate (TDF), a novel nucleotide reverse transcriptase inhibitor (NRTI), was used in patients with HIV co-infected with HBV.

Mesenchymal Migration on Adhesive-Nonadhesive Alternate Surfaces in Macrophages.

Mesenchymal migration usually happens on adhesive substrates, while cells adopt amoeboid migration on low/nonadhesive surfaces. Protein-repelling reagents, e.g.

Construction of a New Immune-Related Competing Endogenous RNA Network with Prognostic Value in Lung Adenocarcinoma.

Tumor microenvironment has significant influence on the gene expression of tumor tissues and on the clinical outcomes in lung adenocarcinoma. Infiltrating immune and stromal cells not only perturb the tumor signal in molecular studies, but also play crucial roles in cancer biology. The competing endogenous RNAs (ceRNAs) are useful to explain the post-transcriptional layer regulated by gene translation and play an important role in the occurrence and progression of lung adenocarcinoma.

Traditional Chinese exercise for non-valvular atrial fibrillation: A protocol for systematic review and meta-analysis.

Introduction: Traditional Chinese exercises have become an important part of cardiac rehabilitation. It can coordinate the essence, qi, and spirit of the human body, and has the functions of promoting joints, stretching muscles and bones, ventilating and blood circulation, so as to achieve the balance between hardness and softness, and between yin and yang. We hope that the research results based on systematic review and meta-analysis will provide a theoretical basis for the treatment of atrial fibrillation (AF) with traditional Chinese exercise.

Efficacy and safety of cutting therapy in the treatment of migraine: A protocol for systematic review and meta-analysis.

Background: Migraine is a chronic paroxysmal neurovascular disease in which pain on one or both sides of the head is the main manifestation and is accompanied by other neurological manifestations. Clinical practice has shown that cutting therapy as a complementary alternative medicine can play a role in relieving migraine attacks. However, there is no consensus on the efficacy of cutting treatment in the treatment of migraine.

Cardioprotective effects of rat adipose‑derived stem cells differ under normoxic/physioxic conditions and are associated with paracrine factor secretion.

Adipose tissue‑derived stem cells (ASCs) are beneficial for myocardial regeneration. The physiological oxygen content of human organs is estimated to range between 1 and 11%. However, in the majority of previous in vitro studies with cultured ASCs, the O2 concentration was artificially set to 21%.

Environmentally friendly remediation of lead/cadmium co-contaminated loess soil in northwestern China using a humificated straw solution.

The remediation of heavy metal-contaminated soils is a great challenge and an important issue for global environmental sciences and engineering. Soil washing technology is popularly used for soil remediation, but there are issues that must be solved. These include selecting an environmentally friendly washing solution and preventing damage to the soil during the washing process.

Remediation of lead and cadmium from simulated groundwater in loess region in northwestern China using permeable reactive barrier filled with environmentally friendly mixed adsorbents.

Permeable reactive barrier (PRB) is potentially effective for groundwater remediation, especially using environmentally friendly mixed fillers in representative areas, such as semi-arid loess region in northwestern China. The mixed materials, including corn straw (agricultural wastes), fly ash (industrial wastes), zeolite synthesized from fly ash (reutilized products), and iron-manganese nodule derived from loess (materials with regional characteristics) in northwestern China, were chosen as PRB media to reduce the contents of lead and cadmium in simulated groundwater. A series of lab-scale column experiments were investigated, and the response surface methodology (RSM) was used to optimize the working process; Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM) were applied to further reveal the reaction mechanism.

[Spectral Characteristics of Dissolved Organic Matter (DOM) Derived from Water and Sediment in Normal Flow Period of the Intersection Zone of Jing River and Wei River].

As the representative component for eco-environmental researchers, dissolved organic matter (DOM) is playing a significant role for the indication effect on environmental quality and efficiency assessment on remediation approaches. Nowadays, it lacks related investigation on DOM derived from rivers and sediments, and the advanced discussion is in urgent need because of the dynamic variations of experimental target, such as spatial-temporal condition, hydrological condition, environmental condition and research dimension. The spectral approaches, including elemental analysis, ultraviolet spectra (UV), Fourier transform infrared spectroscopy (FT-IR), Raman spectra (Raman), three dimensional excitation emission matrix fluorescence spectroscopy (3D-EEMs) and nuclear magnetic resonance (NMR) were used to reveal the characteristics of DOM derived from water and sediment samples in the intersection zone of Jing River and Wei River (Gaoling District, Xi’an City, Shaanxi Province).

[Spectral Evidence of In-Situ Regulatory Mechanisms on Chemical Speciation of Lead/Cadmium Affected by Dissolved Organic Matter Extracted from Rhizosphere Loess of Calendula Officinalis Seedling].

The various characteristics of DOM have great impact on the transformation process of contaminants in soil due to the generation of the feedback regulation in cycles of plant, Rhizosphere soil and environmental contaminants. Currently, more attention was paid on contaminants behaviors of adsorption, transformation, accumulation and detoxification than DOM derived from Rhizosphere soil. The chemical speciation of lead/cadmium and growth efficiency related variations were revealed in the growth process of Calendula officinalis seedlings, and the spectral characteristics of DOM in Rhizosphere loess were discussed with UV, FT-IR and 3D-EEMs spectra.

[Determination of Lead and Cadmium in Calendula Officinalis Seedlings for Phytoremediation of Multi-Contaminated Loess by Using Flame Atomic Absorption Spectrometry with Wet Digestion].

Atomic absorption spectrometry (AAS) is widely used in the analysis and detection of heavy metals. The optimal operation conditions on metals detection are important for the stabilization and repeatability of scientific research, which affects the expected investigation objectives greatly. Thus, it becomes a key issue to establish appropriate detection methods in scientific works.

[FTIR Analysis of Secondary Abiotic Stress Response of Calendula Officinalis Seedlings to Lead and Cadmium in Multi-Contaminated Loess].

As an environmentally-friendly technology attracting great attention from current researchers, phytoremediation is significant for site remediation contaminated by heavy metals. The plant will appear related physiological response to reduce direct harm caused by the stress of heavy metals. The microscale behavior is always multi-dimensional and difficult to detect.

[Response of FTIR and Raman Spectra on Cell Wall of Calendula Officinalis Seedlings Roots to the Co-Contamination Stress of Lead and Cadmium in Loess].

Phytoremediation is a novel method with great potential for site remediation contaminated by heavy metals in future. The cell wall of plant roots is significant to affect the remediation efficiency, for it is related to the multi-interface of heavy metals, pedosphere and plant. The relationship between cell wall of plant and heavy metals is complicated, containing the reaction behavior of physical chemistry, physiology and biochemistry.

[Study on the Mechanism to Ease the Leaching Effect of Nutrient in the Multi-Contaminated Loess Washing Process with the Addition of Anion Adsorbent(Ⅱ)].

The soil washing technology is commonly used to remediate contaminated soils because of its advantages of low cost, ease handling and environmental-friendly. However, it should be noticed that the nutrient might leach simultaneously from soil in the washing process, and the technical solution of the issue will greatly accelerate the application process of washing technology in site remediation. This paper aims to reveal the regulating mechanism of synthesized anion adsorbent from straw on nutrient leaching potential through approaches of adsorption equilibrium models (isotherms and kinetics) and spectral analysis instruments (SEM and FTIR).

[Influence Mechanism of Dissolved Organic Matter (DOM) from Straw Humification on Chemical Speciation of Lead in Loess Region].

Heavy metal is regarded as one of the most representative contaminants in soil, and the chemical speciation is greatly related to the toxicity and transformation behavior, which attracts the attention of researchers for years. The environmental factors could change the speciation of heavy metals, plus to the complexity of soil system, and the transformation variation of speciation might occasional existed under similar conditions. At present, the different viewpoints of related issues are urgent to be investigated.

[Effect of Temperatures and Lead Ions on 3D-EEMs of Dissolved Organic Matter (DOM) Derived from Straw Humification].

Straw incorporation is significant for straw reduction and reutilization, and is clearly required in the twelfth five-year-plan for national economic and social development of the People's Republic of China. The incorporated straw will naturally decompose and release the component of dissolved organic matter (DOM). At present, it lacks the research on straw humification behavior controlled by environmental factors and complexation effect between humification component and metal ions with fluorescence spectrometry in the representative region of loess.

[Effect of pH on the Ultraviolet Spectra and Fluorescence Characteristics of Dissolved Organic Matter in the Process of Straw Humification].

Crop straw is the dominant by-product from agriculture and is regarded as the new source of non-point contamination. Straw incorporation is possible to solve the issues of straw reduction and reutilization, which is clearly required in the twelfth five-year-plan for national economic and social development of the People's Republic of China. At present, it is of noticeable lack of the investigation on straw incorporation behavior and detail humification product analysis in the representative regions under different environmental conditions.

[Spectral Analysis of Dissolved Organic Matter of Tannery Wastewater in the Treatment Process].

Tannery industry is one of the major traditional industries and important wastewater sources in China. The existing research mainly focus on the quality of inlet and outlet water, rather than the purification and transformation behavior of dissolved organic matter (DOM) in the treatment process of tannery wastewater. The UV spectra and fluorescence spectroscopy were used to detect the spectral characteristics of water samples in the treatment process, and it is analyzed that the formation process and the linear relationships between total fluorescence intensity and parameters.

[FTIR and 13C NMR Analysis of Dissolved Organic Matter (DOM) in the Treatment Process of Tannery Wastewater].

Nowadays, the wastewater quantity discharged yearly from tannery industry is around 0. 2 billion t in China. The contaminants of tannery wastewater include macromolecular organic matters, such as grease, fur scraps and collagen, and the alkaline wastewater appears to be of high content of salt and COD.

[Application of Tessier-AAS to the non-biological transformation mechanism of chemical speciation of lead in red soil in agricultural area of central China].

The soil contamination of heavy metals, from the areas of mine, highway, industrial area, agricultural land and so on, is nowadays a serious issue all over the world. The contamination of heavy metals in large agricultural area might lead to the decrease of products quality and economic value. Actually, the accumulation amount of heavy metals by crops is much more related to the activated speciation, which is exchangeable and able to transform to the forms of carbonates, Fe-Mn oxides, organic matter and residual.