[Sacral nerve stimulating on intestinal mucosal immune barrier function of rats with acute complete spinal cord injury].

To study the effects of sacral nerve root stimulation on intestinal mucosal immune barrier function in rat with acute complete spinal cord injury(SCI). Fifty-six Wistar rats were divided into Sham group(SG =8), control group(CG 24 、 48、 72 h,=8), and experimental group(EG 24、 48、 72 h,=8). In CG and EG, according to Fehlings'method,we transected the spinal cord by the aneurysm clip and implanted electrodes into the third sacral foramina on the right side.

[The effects of sacral nerve root electrostimulation on the colon function and its mechanisms in a rat model of spinal cord injury].

Objective: To study the effects of sacral nerve root electrostimulation (SNS) on the colon function and its mechanisms in rats with spinal cord injury (SCI).

Methods: One hundred and four Wistar rats were divided into three groups: A, B and C. A group ( n = 24) was divided into three subgroups (n = 8) for studying the bioelectricity: Normal group (NG), SCI group (SCI) and SCI group with SNS(SNS); B group( n = 24) was divided into three subgroups( n = 8) for studying the colon motility: NG, SCI and SNS.

Ultrastructural study on route of gut bacterial translocation in a rat after spinal cord injury.

Objective: To observe the ultrastructural change of the route of gut bacterial translocation in a rat with spinal cord injury (SCI).

Methods: Forty Wistar rats were divided into the following groups: control group and 3 SCI groups (10 in each group). The rats in the SCI groups were established SCI model at 24 h, 48 h, and 72 h after SCI.

A multicentered prospective analysis of diagnosis, risk factors, and outcomes associated with pediatric ventilator-associated pneumonia.

Objective: To assess risk factors and outcomes associated with pediatric ventilator-associated pneumonia.

Design: Multicentered prospective observational cohort.

Setting: Children's hospitals in the United States.

[The protective effects of sacral nerve electrostimulation on intestinal mucosal mechanical barrier in rats with spinal cord injury].

Objective: To study the protective effects of sacral nerve root electrostimulation on intestinal mechanical barrier in rats with spinal cord injury (SCI).

Methods: Fifty six Wistar rats were divided into normal group, SCI control group and SCI group with sacral nerve root electrostimulation (8 rats in each subgroup at 24, 48, 72 h after spinal cord injury). The following experiments were performed respectively in rats from the 3 groups: bacteria culture from intestinal mesentery lymph nodes, liver, spleen, intestinal morphology observation and detection the protein expression level of ZO-1.

Influence of S₃ electrical stimulation on gastrointestinal dysfunction after spinal cord injury in rabbits.

Objective: To investigate the effect of electrical stimulation to sacral spinal nerve 3 (S₃ stimulation) on gastrointestinal dysfunction after spinal cord injury (SCI).

Methods: Six rabbits were taken as normal controls to record their gastrointestinal multipoint biological discharge, colon pressure and rectoanal inhibitory reflex. Electrodes were implanted into S₃ in another 18 rabbits.

Comparison of activity level among patients with chronic liver disease.

Purpose: To determine whether self-reported maximal and daily activity levels are impaired among patients with nonalcoholic fatty liver disease (NAFLD), hepatitis C (HCV) and hepatitis B (HBV).

Methods: Clinicodemographic, diagnostic, self-report and standard laboratory data were obtained. Univariate, multivariate and regression analyses were performed comparing group maximal (Maximum Activity Score [MAS]) and daily activity scores (Adjusted Activity Score [AAS]), adjusted for age and gender.

Efficacy and safety of surgery for lumbar disc herniation in patients aged 80 and older.

Aim: To evaluate the efficacy and safety of surgery for lumbar disc herniation in patients aged 80 or older.

Material And Methods: Operative time (OT), intraoperative estimated blood loss (EBL), length of hospital stay (LOS), and complication rate (CR) were used to assess safety of surgery. The Visual Analog Scale (VAS), the Oswestry disability index (ODI) and the North American Spine Society Outcome Questionnaire (NASS-Q) were used to evaluate the clinical effectiveness.

Long-term follow-up of patients with nonalcoholic fatty liver.

Background & Aims: Nonalcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of conditions ranging from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH) convincingly. NASH is the only subtype of NAFLD that has been shown to progress relatively, although these findings were reported from studies with short follow-up periods. We assessed the long-term outcomes of a NAFLD cohort.

Apnoeic-hypopnoeic episodes during obstructive sleep apnoea are associated with histological nonalcoholic steatohepatitis.

Background: Nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnoea are associated with metabolic syndrome and atherosclerotic heart disease. This study evaluates the potential association between the NAFLD subtypes and a number of polysomnographical (PSG) parameters.

Methods: This study included patients undergoing bariatric surgery with extensive clinical and histological data for whom complete PSG data before surgery were also available.

Nutritional assessments of patients with non-alcoholic fatty liver disease.

Background: Obesity is not only associated with nonalcoholic fatty liver disease (NAFLD) but it also adversely affects the progression of other liver diseases. There are limited data regarding the dietary habits of patients with chronic liver disease.

Methods: Nutrition surveys containing 13 different food groups were mailed.

Metabolic syndrome after laparoscopic bariatric surgery.

Background: Metabolic syndrome (MS) is common among morbidly obese patients undergoing bariatric surgery. The aim of this study was to assess the impact and predictors of bariatric surgery on the resolution of MS.

Methods: Subjects included 286 patients [age 44.