Synopsis of recent research by authors named "Chung-Yee Yuo"
- Chung-Yee Yuo's research extensively focuses on genetic and molecular mechanisms underlying various neuromuscular diseases, particularly spinal muscular atrophy (SMA) and congenital muscular dystrophy (CMD), with investigations into pathogenic gene mutations and potential therapeutic targets.
- The studies reveal significant insights, such as the role of SMN2 exon 7 inclusion mediating motor neuron survival in SMA, and a significant novel mutation associated with limb-girdle muscular dystrophy, enhancing understanding of disease phenotypes in the Taiwanese population.
- Yuo also delves into the functional implications of pseudogenes and non-coding RNAs in oncogenesis, emphasizing how these genetic elements can influence tumor growth and gene regulation, thereby expanding the scope of genetic research in both neuromuscular and oncological contexts.
