Comparison of Radioactive Seed Localized Excision and Wire Localized Excision of Breast Lesions: A Community Hospital's Experience.

Background: Most data comparing wire localized excision (WLE) and radioactive seed localized excision (RSLE) derive from academic institutions with limited data from community hospitals. This study aimed to compare positive margin rates between WLE and RSLE and to determine if there were any differences in specimen volume and operation time.

Patients And Methods: A retrospective cohort study was conducted on patients who underwent WLE or RSLE at a Canadian community hospital.

Parathyroid nodules in a patient with chronic renal failure: Hyperplasia or neoplasia?

Enlarged parathyroid glands found at autopsy in a 69-year-old-old man with chronic renal failure and hyperparathyroidism were examined and compared with his parathyroidectomy specimens from 5 years previously. Histology, immunohistochemistry, and DNA analysis did not discriminate conclusively between nodular hyperplasia and adenoma. Although transformation of parathyroid hyperplasia to adenoma remains an attractive hypothesis, conclusive distinction between dependent secondary hyperparathyroidism and autonomous tertiary hyperparathyroidism cannot be made at present on the basis of morphology.